The data are presented which supporting the hypothesis of the presence of isometric force load zone, within which the subjects tested organize the voluntary muscle tension controlling with maximal accuracy and minimal specific power expenses, estimated indirectly, by the ratio of the surface electromyogram (EMG) area (integral of EMG) to force moment impulse. The asymmetries of the integral values of visual-and-motor tracking have been analyzed as well using isometric control organs in 23 patients at the age of 15-35 years (6 - males and 17 - females) in different periods after surgical elimination of lower limb length discrepancies. Poorly marked zone of minimization of integral discrete visual-and-motor tracking estimates, manifesting itself within 25-35% of the maximal force of the muscle group tested (foot dorsal flexors) has been noted in tested healthy subjects (26 normal males at the age of 19-39 years) and orthopedic patients (intact limb). The zone of "optimal' loads is marked more clearly on patients' lengthening side with the tendency towards its shift to the area of weaker forces.
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Sci Rep
January 2025
School of Civil Engineering, Hunan City University, Yiyang, China.
To investigate the dynamic characteristics and safe operation speed threshold of metro train passing through curved bridge (CB) considering resilient wheels, the mechanical connection characteristics of rim and web are discussed firstly. Based on the train-track-bridge interaction theory, the coupled dynamic model of metro train-CB considering resilient wheels is established. Then, the vehicle-bridge coupled dynamic characteristics under the excitation of long-short wave track irregularity are researched.
View Article and Find Full Text PDFMicrobiol Spectr
January 2025
Center for Infectious Diseases, Lab of Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.
Unlabelled: Due to increasing antimicrobial resistance and side effects caused by current standard antimicrobial regimens used for treatment of prosthetic joint infection (PJI), alternative options are urgently needed. We aimed to investigate the effect of clindamycin in different exposure strategies against in an mature biofilm model. In short, 7-day biofilms were generated on polystyrene plates and titanium-aluminum-vanadium discs using a clinical PJI isolate.
View Article and Find Full Text PDFMyoelectric prosthetic hands are typically controlled to move between discrete positions and do not provide sensory feedback to the user. In this work, we present and evaluate a closed-loop, continuous myoelectric prosthetic hand controller, that can continuously control the position of multiple degrees of freedom of a prosthesis while rendering proprioceptive feedback to the user via a haptic feedback armband. Twenty-eight participants without and ten participants with upper limb difference (ULD) were recruited to holistically evaluate the physical and psychological effects of the controller via isolated control and sensory tasks, dexterity assessments, embodiment and task load questionnaires, and post-study interviews.
View Article and Find Full Text PDFPhytomedicine
January 2025
Heilongjiang Key Laboratory for Animal Disease Control and Pharmaceutical Development, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China. Electronic address:
Background: Staphylococcus aureus is an opportunistic pathogen capable of readily forming biofilms, which can result in life-threatening infections involving different organs. Sanguinarine are benzo[c]phenanthridine alkaloids extracted from the Sanguinaria canadensis L. (Papaveraceae), which have a wide range of biological activities.
View Article and Find Full Text PDFJ Sports Sci
January 2025
Department of Movement, Human and Health Sciences, University of Rome "Foro Italico", Rome, Italy.
Anticipatory postural adjustments (APAs) are responsible for a successful first step execution in handstand walking. This study evaluates gymnasts' ability to adapt their APAs and stepping parameters in response to adding/removing an external load over repeated handstand walking initiation trials. Eighteen gymnasts performed five handstand walking initiation trials without load (PRE), eight trials with an external load (LOAD) and five trials with removed load (POST).
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