A vegetative mass in the right nasal cavity of a 62-year-old man from Palma de Mallorca, Spain, was found to be due to Leishmania. The organism was isolated in culture and characterized by in situ hybridization, Southern blot hybridization, and isoenzyme analysis; it was thus demonstrated to be the most common enzyme variant 1 (MON 1) of Leishmania (Leishmania) infantum.
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http://dx.doi.org/10.4269/ajtmh.1990.43.614 | DOI Listing |
mSphere
January 2025
Department of Biological Sciences, University of Cincinnati, Cincinnati, Ohio, USA.
Miguel Chiurillo works in the field of protein kinases, studying their role in cell signaling and cell cycle progression in . In this mSphere of Influence article, he reflects on how the research articles "Systematic functional analysis of protein kinases identifies regulators of differentiation or survival" by Baker et al. and "Screening the kinome with high throughput tagging identifies a regulator of invasion and egress" by Smith et al.
View Article and Find Full Text PDFmSphere
January 2025
Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA.
Visceral leishmaniasis (VL) is a vector-borne disease caused by the obligate intracellular protozoan in India. VL can be complicated by post-kala-azar dermal leishmaniasis (PKDL), a macular or nodular rash that develops in 10%-20% of patients after treatment of VL in India. Patients with PKDL are infectious to sand flies, promoting further transmission of the parasite.
View Article and Find Full Text PDFParasit Vectors
January 2025
Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, Avda. Puerta de Hierro S/N, 28040, Madrid, Spain.
Background: In recent years, cases of leishmaniosis have been described in animals housed in captivity in zoos in Spain [Bennett's wallaby (Macropus rufogriseus rufogriseus), orangutan (Pongo pygmaeus pygameus), and European otter (Lutra lutra)]. Some of these zoological parks are in endemic areas for both human and animal leishmaniosis, thus it should be very important to include this zoonosis in the differential diagnosis.
Methods: The study was carried out in two zoological parks in Madrid, Madrid Zoo and Faunia, and analyzed seven meerkats.
PLoS Negl Trop Dis
January 2025
Department of Zoology and Environment Management, Faculty of Science, University of Kelaniya, Dalugama, Sri Lanka.
Background: Leishmaniasis is a health problem in many regions with poor health and poor life resources. According to the World Health Organization (WHO), an estimated 700,000-1 million new cases arise annually. Effective control of sand fly vector populations is crucial for reducing the transmission of this disease.
View Article and Find Full Text PDFPak J Med Sci
January 2025
Khalid Rehman Institute of Public Health & Social Sciences, Khyber Medical University, Peshawar, Pakistan.
Objective: To determine the impact of leishmaniasis on the quality of life of patients visiting the district headquarter hospital in District Khyber, Khyber Pakhtunkhwa, Pakistan.
Methods: A cross-sectional exploratory study was conducted in District Headquarter Hospital of Khyber District, Khyber Pakhtunkhwa from November 2019 to April 2020. In this study, 349 participants who consented were included by using a non-probability consecutive sampling technique.
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