Bone sarcomas are uncommon tumours, of which osteosarcoma is the least rare, as well as the third most common malignant tumour in childhood, appearing usually between the 10 and 20 years of age. The case the authors present in this work is of a patient suffering from a long-standing condition encompassing skin and soft tissue lesions. After multiple medical treatments, the patient was diagnosed with squamous osteosarcoma, which required aggressive surgical management and chemotherapy.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229320PMC
http://dx.doi.org/10.1136/bcr.06.2011.4413DOI Listing

Publication Analysis

Top Keywords

osteoblastic fibroblastic
4
fibroblastic multicentric
4
multicentric osteosarcoma
4
osteosarcoma bone
4
bone sarcomas
4
sarcomas uncommon
4
uncommon tumours
4
tumours osteosarcoma
4
osteosarcoma rare
4
rare well
4

Similar Publications

Periimplantitis represents an inflammatory disease of the soft and hard tissues surrounding the osseointegrated dental implant, triggering progressive damage to the alveolar bone. Cumulative data have revealed that periimplantitis plays a crucial part in implant failure. Due to the strategic roles of autophagy and its upstream coordinator, the AKT/mTOR pathway, in inflammatory responses, the crosstalk between them in the context of periimplantitis should become a key research target, as it opens up an area of interesting data with clinical significance.

View Article and Find Full Text PDF

Multifaceted roles of IL-17 in bone and tendon health.

Int J Biol Macromol

January 2025

Department of Orthopedics, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan 646000, China. Electronic address:

The interleukin-17 (IL-17) family, encompassing IL-17A to IL-17F, plays pivotal roles across various biomedical fields. IL-17A, a prominent cytokine, has garnered significant attention. However, the pathological effects of IL-17 can often be unpredictable.

View Article and Find Full Text PDF

Background: Diode laser is known for its biostimulatory effects on various cell populations such as osteoblasts and fibroblasts. The usage of low-level laser therapy for photobiomodulation depends on its type, emission wavelength, and energy selected. Previously performed studies have determined its effect on cell proliferation and cytotoxicity; however, the results were inconsistent.

View Article and Find Full Text PDF

Integrated transcriptomic analysis reveals evolutionary and developmental characteristics of tendon ossification in teleost.

BMC Biol

December 2024

College of Fisheries, Hubei Hongshan Laboratory/Key Lab of Freshwater Animal Breeding, Ministry of Agriculture and Rural Affairs/Engineering Research Center of Green Development for Conventional Aquatic Biological Industry in the Yangtze River Economic Belt, Ministry of Education, Huazhong Agricultural University, No. 1 Shizishan Street, Hongshan District, Wuhan, 430070, Hubei, China.

Background: Intermuscular bones (IBs) are segmental intramembranous ossifications located within myosepta. They share similarities with tendon ossification, a form of heterotopic ossification (HO). The mechanisms underlying IB formation remain incompletely understood.

View Article and Find Full Text PDF

Inflammation and mechanical force-induced bone remodeling.

Periodontol 2000

December 2024

Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Article Synopsis
  • Periodontitis results from an imbalance between host immune responses and microbial interactions, leading to inflammation and loss of bone structure.
  • The transition from gingivitis to periodontitis may be influenced by inflammation's proximity to bone, affecting bone resorption and formation.
  • Recent research using single-cell RNA sequencing has revealed the distinct roles of various cell types in inflammation and bone remodeling, highlighting the complex interactions in conditions like periodontitis and orthodontic movement.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!