Hippocampal sequences link past, present, and future.

Trends Cogn Sci

Graduate Program in Neuroscience, University of Minnesota, Minneapolis, MN 55455, USA.

Published: July 2012

Disrupting the reactivation of hippocampal neurons during sleep impairs memory consolidation in rats. However, the functional importance of reactivation during awake states is unknown. An experiment in which awake reactivation was disrupted suggests that this phenomenon could adaptively guide behavior by linking previous learning with the current state of the world.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015726PMC
http://dx.doi.org/10.1016/j.tics.2012.05.005DOI Listing

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