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Introduction: Tobacco use typically begins during adolescence. There is a lack of comprehensive evidence on the use of different tobacco products among adolescents in Africa.

Aims And Methods: We used the most recent Global Youth Tobacco Surveys from 53 African countries, covering 2003-2020, to estimate the overall and gender-specific prevalence of each type of tobacco product by country, Africa region, World Bank income group, and age group among adolescents aged 11-17 years.

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AAV Capsid Modification and Its Influence on Viral Protein Stoichiometry and Packaging Fitness: Current Understandings and Future Direction.

Mol Biotechnol

January 2025

Medical Biotechnology and Immunotherapy Research Unit, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, 7700, South Africa.

The field of gene therapy has witnessed significant advancements in the utilization of Adeno-associated virus (AAV) owing to its inherent biological advantages. Targeted AAV vectors are generated through genetic or chemical modification of the capsid for user-directed purposes. However, this process can result in imbalances in viral protein sequence homogeneity, stoichiometry, and functional transduction vector units, thereby introducing new challenges.

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Introduction: Emergency care begins in the community, who are often the first on the scene. Where emergency care systems are nascent or absent, bystanders represent the only prehospital emergency care that victims might receive. It is important to equip bystanders through life-saving skills training (LST).

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Clinical Relevance: Hyperopia is a common refractive error in young children and has the potential to affect their visual, educational and general development. Management of childhood hyperopia presents significant intra-and inter-professional differences partly because evidence-based guidelines to inform when and how to prescribe for hyperopia are insufficient.

Purpose: This study investigated the prescribing philosophy in childhood hyperopia among optometrists in Ghana and the challenges faced in managing childhood hyperopia.

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Background: Nurses play a pivotal role in the provision of health care for children across Africa. With limited pediatric nursing content in undergraduate nursing programs and few available pediatric postgraduate nursing programs, there is a need for additional continuing professional development opportunities to prepare nurses with the knowledge, skills, and confidence needed to care for children.

Method: To address this need, and mindful of the unique profile of potential participants, the Children's Nursing Development Unit at the University of Cape Town developed a suite of asynchronous short online courses.

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