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Early Detection of Testicular Sertoli Cell Tumor Through Physical Examination: A Case Report.
Cureus
December 2024
Medical Corps, Israel Defense Forces, Haifa, ISR.
Testicular tumors represent the most common solid organ malignancy in young and adult males. Sex cord-stromal tumors are the second-largest group of primary testicular cancers, after germ-cell tumors. Sertoli cell (SC) tumors of the testis are relatively rare, accounting for only a small fraction of testicular tumors.
View Article and Find Full Text PDFReconstruction of a rostral maxillary defect by two custom-made titanium implants following a partial maxillectomy for treatment of squamous cell carcinoma in a dog.
Vet Res Commun
January 2025
Veterinary Teaching Hospital, Complutense University of Madrid, Avda. Puerta de Hierro s/n, Madrid, 28040, Spain.
This case report describes the reconstruction of a rostral maxillary defect by two custom-made titanium implants following a rostral partial maxillectomy for treatment of squamous cell carcinoma (SCC) in a seven-year-old dog. An incisional biopsy and CT scan were performed to establish the diagnosis, to plan possible surgery, and to assess the margins of the tumour. The patient had no radiographic signs of metastasis at the time of diagnosis.
View Article and Find Full Text PDFOral Blue Nevus of the Lingual Gingiva: A Case Report.
Cureus
January 2025
College of Dentistry, King Saud University, Riyadh, SAU.
Oral melanocytic nevi (OMN) are rare benign tumors originating from melanocytes with an unclear pathogenesis. The current theory suggests that OMN originate from dormant dendritic melanocytes that become enclosed in the dermis during the embryonic migration of melanoblasts - the precursors of melanocytes - from the neural crest to the epidermis. OMN can be congenital or acquired, with acquired nevi being more common.
View Article and Find Full Text PDFBaicalin attenuates the immune escape of oral squamous cell carcinoma by reducing lactate accumulation in tumor microenvironment.
J Adv Res
January 2025
Department of General/Emergency, Tianjin Medical University School and Hospital of Stomatology & Tianjin Key Laboratory of Oral Soft and Hard Tissues Restoration and Regeneration, No.12 Qixiangtai Road, Heping District, Tianjin 300070, China; Tianjin Medical University Institute of Stomatology, No.12 Qixiangtai Road, Heping District, Tianjin 300070, China. Electronic address:
Introduction: The acidic microenvironment caused by excessive lactate accumulation could inhibit immune lymphocytes antitumor activity and promote the immune escape of tumor cells. Baicalin is an active flavonoid isolated from Scutellaria baicalensis Georgi, a traditional Chinese medicinal herb with antioxidant and anti-inflammatory properties.
Objectives: The present study aims to investigate whether and how baicalin inhibits oral squamous cell carcinoma (OSCC) acidic microenvironment and attenuates immune escape.
Bilateral inverted papilloma: Case report and literature review.
Radiol Case Rep
March 2025
Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, Morocco.
Inverted papilloma is a rare, benign epithelial tumor of the nasal and sinus cavities with an unclear etiology. It usually presents as unilateral nasal obstruction. Diagnosis is histological, and treatment is primarily surgical.
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