The accommodation function was examined before and after flight by the method of ophthalmoergometry. During flight proximetric measurements were performed according to the routine method. Medical examinations of cosmonauts following short- and long-term flights demonstrated that the main visual functions remained adequate. The changes included the development of eye fatigue caused by visual load, complexity of visual tasks and unfavorable conditions of visual perception as well as decrease of the accommodation range, peripheral and central visual fatigue. These changes persisted during several days after flight. It is concluded that the crewmembers with an inadequate accommodation function should use methods of optic correction. The detection of the above changes indicates the necessity of prophylaxis of eye fatigue in order to maintain visual work capacity.
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Med J Armed Forces India
April 2024
Senior Advisor (Medicine) & Gastroenterologist, Command Hospital (Southern Command), Pune, India.
Background: Acute-on-chronic liver failure (ACLF) is a life threatening disease. This study seeks to identify factors that contribute to greater financial burden in ACLF.
Methods: In total, 55 patients were included.
Int J Nephrol Renovasc Dis
January 2025
Nephrology Unit, University Hospital of Ferrara, Ferrara, Italy.
Purpose: Social determinants of health have been related with kidney diseases and their outcomes. Financial toxicity (FT) refers to the negative impact of health care costs on clinical conditions. This scoping review aimed to evaluate the literature linking FT with renal diseases.
View Article and Find Full Text PDFCurr Eye Res
January 2025
Department of Ophthalmology, Duke University, Durham, NC, USA.
Purpose: Central retinal artery occlusion, also known as an eye stroke, results in visual impairment and functional challenges. Our study objectives were to identify meaningful measures and factors that indicate or enable successful recovery after eye stroke and to determine optimal processes to support research, including exploring barriers and facilitators to successful research participation.
Methods: We used qualitative methods including the 5Ts Framework (target population identification, team composition, time considerations, tips to accommodate older adults, tools for inclusive enrollment of older adults) to provide a guide to the development of the semi-structured interviews and to help facilitate the research process such as the set-up of interviews.
PLoS One
January 2025
Department of Statistics and Probability, Michigan State University, East Lansing, MI, United States of America.
The genetic basis of complex traits involves the function of many genes with small effects as well as complex gene-gene and gene-environment interactions. As one of the major players in complex diseases, the role of gene-environment interactions has been increasingly recognized. Motivated by epidemiology studies to evaluate the joint effect of environmental mixtures, we developed a functional varying-index coefficient model (FVICM) to assess the combined effect of environmental mixtures and their interactions with genes, under a longitudinal design with quantitative traits.
View Article and Find Full Text PDFReading, face recognition, and navigation are supported by visuospatial computations in category-selective regions across ventral, lateral, and dorsal visual streams. However, the nature of visuospatial computations across streams and their development in adolescence remain unknown. Using fMRI and population receptive field (pRF) modeling in adolescents and adults, we estimate pRFs in high-level visual cortex and determine their development.
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