AI Article Synopsis
- - The study reports the identification and analysis of three vancomycin-resistant Enterococcus faecalis isolates carrying the vanB1 gene.
- - These isolates showed resistance mainly to chloramphenicol, erythromycin, and vancomycin, but were generally susceptible to other antimicrobial agents, with significant resistance to aminoglycosides.
- - This is the first documented instance of enterococcal strains with vanB genes being found in Brazil, highlighting a potential public health concern.
Article Abstract
Here we describe the detection and characterisation of three isolates of vancomycin-resistant VanB-type Enterococcus faecalis. Sequence analysis suggested that these isolates harboured the vanB1 gene. The isolates were susceptible to the majority of antimicrobial agents tested, with the exception of chloramphenicol, erythromycin and vancomycin, and showed distinct profiles of high-level resistance to aminoglycosides. Analysis of the clonal relatedness of the vanB E. faecalis isolates showed similar pulsed-field gel electrophoresis profiles. To our knowledge, this is the first report of the occurrence of enterococcal strains carrying vanB genes in Brazil.
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| http://dx.doi.org/10.1590/s0074-02762012000400020 | DOI Listing |
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