Objective: To evaluate the secular trend of menarche according to body mass index (BMI).
Subjects And Methods: Six hundred and eighty five girls (7-18 years) assessed in 2001 were compared with 750 evaluated in 2010. They were grouped by BMI Z-score: (thin + normal) and (overweight + obese). Menarche was reported by status quo and age at menarche estimated by a logit model. We used the Qui-square test, Mann-Whitney test, and Logistic Regression, at a 5% significance level.
Results: Menarche advanced 3.24 months. There was an increase in obesity, and a decrease of the prevalence of normal girls. Menarche was anticipated by 1.44 month in the thin + normal group and by 5.76 months in the overweight + obese group. There was no interaction between the effects determined by the evaluated period and nutritional diagnosis.
Conclusions: Although both the period and BMI influence the menarche, one cannot attribute this advance only to changes in the nutritional profile of the sample. Other factors that were not tested may also contribute to this finding.
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http://dx.doi.org/10.1590/s0004-27302012000300008 | DOI Listing |
Menopause
January 2025
Department of Child, Family, and Population Health Nursing, University of Washington, Seattle, WA.
Objective: This study aimed to determine whether exposure to traffic-related air pollution (TRAP) is associated with depressive symptoms while also characterizing the contribution of key explanatory factors related to sociodemographics and health. In addition, it aimed to also explore the role of reproductive health as a pathway through which exposure to TRAP may relate to depressive symptoms.
Methods: Participants were 688 healthy reproductive-age women in the Ovarian Aging Study.
Cancer Res Commun
January 2025
University Hospitals Leuven, Leuven, Belgium.
This study evaluated the association between age at first full-term pregnancy (FFTP) and mammographic breast density (MBD) in postmenopausal women. 1,034 women, age 50-69y, were recruited from the Flemish (Belgium) population-based breast cancer screening program. Participants completed a questionnaire on lifestyle and reproductive factors.
View Article and Find Full Text PDFJ Reprod Infertil
January 2024
Departments of Anatomy and Physiology, Edo State University Uzairue, Auchi, Nigeria.
The impact of artificial light exposure on human health has garnered significant attention in recent years. In particular, its effects on reproductive health have raised concerns. Given that the onset of menarche serves as a crucial indicator of reproductive maturity, understanding the implications of artificial light exposure becomes paramount.
View Article and Find Full Text PDFInt J Fertil Steril
January 2025
Jubilee Centre for Medical Research, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India. Email:
Background: Polycystic ovary syndrome (PCOS) is one of the most prevalent endocrine conditions that significantly impact the life quality of reproductive-aged women. In the Indian population, its prevalence varies from 3.7 to 22.
View Article and Find Full Text PDFNat Commun
January 2025
Laboratory of Molecular Translational Medicine, Center for Translational Medicine, West China Second University Hospital, Sichuan University, Chengdu, China.
Pubertal timing is highly variable and is associated with long-term health outcomes. Phenotypes associated with pubertal timing include age at menarche, age at voice break, age at first facial hair and growth spurt, and pubertal timing seems to have a shared genetic architecture between the sexes. However, puberty phenotypes have primarily been assessed separately, failing to account for shared genetics, which limits the reliability of the purported health implications.
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