Familial early onset of type-2 diabetes mellitus and its complications.

N Am J Med Sci

Diabetes Centre & Department of Medicine, K.L.E.S Dr. Prabhakar Kore Hospital & Medical Research Centre & Jawaharlal Nehru Medical College, KLE University, Belgaum- 590010, Karnataka, India.

Published: December 2009

Background: Globally, the prevalence of chronic, non-communicable diseases is increasing at an alarming rate. Furthermore, approximately 197 million people worldwide have impaired glucose tolerance. Consequently, diabetes is rapidly emerging as a global health problem that threatens to assume a pandemic level by 2030. In Indian population, genetic predisposition to trigger diabetes at an early age as compared to western counterpart has been focused very much.

Aim: To gain further insight into the positive correlation between the diabetes and family history was the objective of this study.

Materials And Methods: Patients attending the Diabetes Centre, K.L.E.S Dr. Prabhakar. Kore Hospital and Medical Research Centre; J. N. Medical College; KLE University Belgaum, Karnataka- India, were recruited, diagnosed and analyzed as per WHO criteria.

Results: The prevalence of diabetes was higher among patients with diabetic mother (25.6%) compared to patients with diabetic father (21.2%) and there was early onset of type -2 diabetes among patients having both parents with diabetic when compared to other patients.

Conclusion: Based on the present observation, it would be appropriate to emphasize again that a strong family history for diabetes, would signal at an early age, the onset of diabetes perhaps with its complications.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364686PMC
http://dx.doi.org/10.4297/najms.2009.7377DOI Listing

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