This paper reports on the transformation that has occurred in the care of people living with HIV/AIDS in a Toronto Hospice. Casey House opened in the pre-HAART era to care exclusively for people with HIV/AIDS, an incurable disease. At the time, all patients were admitted for palliative care and all deaths were due to AIDS-defining conditions. AIDS-defining malignancies accounted for 22 percent of deaths, mainly, Kaposi sarcoma and lymphoma. In the post-HAART era, AIDS-defining malignancies dropped dramatically and non-AIDS-defining malignancies became a significant cause of death, including liver cancer, lung cancer and gastric cancers. In the post-HAART era, people living with HIV/AIDS served at Casey House have changed considerably, with increasing numbers of patients facing homelessness and mental health issues, including substance use. Casey House offers a picture of the evolving epidemic and provides insight into changes and improvements made in the care of these patients.
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http://dx.doi.org/10.1155/2012/390406 | DOI Listing |
Environ Epidemiol
February 2025
Department of Sociomedical Sciences, Mailman School of Public Health, Columbia University, New York, New York.
Background: Utility services for electricity, gas, heat, and hot water are necessities for everyday activities (e.g., lighting, cooking, and thermal safety).
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December 2024
Dogs Trust, London, UK.
There is limited knowledge about the size of the UK dog population. This makes it difficult to reliably monitor population dynamics and management. A repeatable method of measuring the UK dog population, including owned and unowned dogs i.
View Article and Find Full Text PDFAnim Welf
December 2024
Dogs Trust, London EC1V 7RQ, UK.
Separation-related behaviours (SRBs) in dogs () often indicate poor welfare. Understanding SRB risk factors can aid prevention strategies. We investigated whether early-life experiences and dog-owner interactions affect SRB development.
View Article and Find Full Text PDFJAMA
December 2024
Warwick Medical School, Clinical Trials Unit, University of Warwick, Coventry, United Kingdom.
Importance: For hospitalized critically ill adults with suspected sepsis, procalcitonin (PCT) and C-reactive protein (CRP) monitoring protocols can guide the duration of antibiotic therapy, but the evidence of the effect and safety of these protocols remains uncertain.
Objective: To determine whether decisions based on assessment of CRP or PCT safely results in a reduction in the duration of antibiotic therapy.
Design, Setting, And Participants: A multicenter, intervention-concealed randomized clinical trial, involving 2760 adults (≥18 years), in 41 UK National Health Service (NHS) intensive care units, requiring critical care within 24 hours of initiating intravenous antibiotics for suspected sepsis and likely to continue antibiotics for at least 72 hours.
Can Pharm J (Ott)
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Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario.
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