The aim of this study was to know the constraining and facilitating aspects of adherence to highly active antiretroviral therapy (HAART) among people with HIV/AIDS. This was a qualitative study, carried out with 26 individuals receiving HAART and assisted by a referral service in Belo Horizonte, Minas Gerais, Brazil. The analysis of the interviews regarding the constraints found by users, resulted in categories relating to Day-by-day life, HIV representations, and the complexity of the treatment. As for the facilitating aspects, the categories found were absence of side effects, remembering the symptoms of the disease, improved survival, and influences from the social networks. Results have shown the importance of an effective follow-up so that health care professionals can build strategies to improve adherence to HAART together with the individuals.
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http://dx.doi.org/10.1590/s0034-71672011000600007 | DOI Listing |
Ann Vasc Surg
January 2025
Department of Medical and Surgical Sciences, Magna Graecia University of Catanzaro, 88100, Catanzaro, Italy; Interuniversity Center of Phlebolymphology (CIFL), "Magna Graecia" University, 88100 Catanzaro, Italy. Electronic address:
Background: Arterial diseases like coronary artery disease, carotid stenosis, peripheral artery disease, and abdominal aortic aneurysm have high morbidity and mortality, making them key research areas. Their multifactorial nature complicates patient treatment and prevention. Biomarkers offer insights into the biochemical and molecular processes, while social factors also significantly impact patients' health and quality of life.
View Article and Find Full Text PDFArch Gynecol Obstet
January 2025
Division of Gynaecological Endocrinology and Reproductive Medicine, University Hospital Inselspital, Bern, Switzerland.
Purpose: Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age, often leading to anovulatory infertility. Obesity exacerbates the reproductive, metabolic and psychological features of PCOS, making fertility treatment and patient satisfaction difficult. Despite guidelines from the European Society of Human Reproduction and Embryology (ESHRE) emphasizing lifestyle modifications and specific treatments, there remains a significant gap in adherence to these guidelines by both healthcare providers and patients.
View Article and Find Full Text PDFPharmaceutics
December 2024
Department of Pharmacy, University of Huddersfield, Huddersfield HD1 3DH, UK.
Spironolactone (SP), an aldosterone inhibitor widely used to treat androgen-dependent disorders such as acne, hirsutism, and alopecia, has demonstrated therapeutic potential in both oral and topical formulations. However, SP's low solubility and poor bioavailability in conventional formulations have driven the development of novel nanocarriers to enhance its efficacy. This review systematically examines recent advancements in SP-loaded nanocarriers, including lipid nanoparticles (LNPs), vesicular nanoparticles (VNPs), polymeric nanoparticles (PNPs), and nanofibers (NFs).
View Article and Find Full Text PDFNutrients
January 2025
Sports Medicine Centre, University of Florence, 50121 Firenze, Italy.
Background: Recent research emphasizes the importance of integrating psychological-emotional factors with nutrition and body composition in athletes. This study investigates the correlations between these aspects in 36 professional rugby players, aiming to identify relationships that could optimize sports performance and overall well-being.
Methods: The study sample included 36 male athletes (mean age: 24.
Pathogens
January 2025
Biomedical Sciences Laboratory (CBMU), School of Medicine, Universidad de Los Andes, Bogotá D.C 111711, Colombia.
, the etiological agent of Chagas disease, is a parasite known for its diverse genotypic variants, or Discrete Typing Units (DTUs), which have been associated with varying degrees of tissue involvement. However, aspects such as parasite attachment remain unclear. It has been suggested that the TcI genotype is associated with cardiac infection, the most common involved site in chronic human infection, while TcII is associated with digestive tract involvement.
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