There are a number of important issues for the dairy practitioner to consider in designing the most appropriate mastitis microbiological service for his or her clients. These include the decision to use enhancement tools or selective agars to optimize sensitivity and specificity. The service should include a monthly BTC service that monitors for the important contagious mastitis organisms: S aureus, S agalactia, and Mycoplasma. At the cow level, a zero tolerance program to protect healthy cows from exposure to contagious mastitis will require a routine culture service to monitor for these pathogens in new herd additions, clinical cases, and all fresh cows and heifers. A wide variety of additional benefits for maintaining good udder health and the production of quality milk can come from a more comprehensive diagnostic service that looks at both individual cow and bulk tank milk. Finally, more practitioners can help their clients economically by implementation of an on-farm TNT culture service and significantly reducing the use of intramammary therapy.
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http://dx.doi.org/10.1016/j.cvfa.2012.03.006 | DOI Listing |
JDS Commun
November 2024
Department of Large Animal Clinical Sciences, Michigan State University, East Lansing, MI 48824.
The objective of this observational study was to estimate partial direct costs of dry cow antibiotic therapy (DCT) protocols used on 37 large dairy herds in Wisconsin and to estimate the potential monetary savings and reduction in antimicrobial usage (AMU) if selective DCT was used. Partial direct costs of DCT were calculated using costs of intramammary (IMM) antimicrobials and teat sealants. Data were retrospectively collected on 37 large dairy farms for a period of 1 yr and included the total number of cows dried off, types of IMM antimicrobial used, and product prices (obtained from farm invoices).
View Article and Find Full Text PDFRes Vet Sci
January 2025
Dipartimento di Medicina Veterinaria e Scienze Animali - DIVAS, Università degli Studi di Milano, 26900 Lodi, Italy; Laboratorio di Malattie Infettive degli Animali (MiLab), Università degli Studi di Milano, 26900 Lodi, Italy. Electronic address:
Staphylococcus aureus is the main etiologic agent of contagious dairy cow mastitis, while non-aureus staphylococci and mammaliicocci (NASM) are the bacteria most frequently isolated from milk. Beyond their impact on animal health, NASM can harbor antimicrobial resistance (AMR) genes with potential for bidirectional transfer with S. aureus, and methicillin-resistant (MR) staphylococci (MRS) can raise significant One Health concerns.
View Article and Find Full Text PDFJ Antimicrob Chemother
November 2024
Department of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, WI, USA.
Background: Bovine mastitis is the costliest disease in the dairy sector and the main cause of antibiotic use in dairy cattle, potentially contributing to the antimicrobial resistance crisis. Antimicrobial peptides (AMPs) offer promise as antibiotic alternatives for controlling mastitis pathogens.
Methods: The efficacy of five AMPs (Lynronne-1 [Lyn-1], Lynronne-2 [Lyn-2], Bovicin HC5, AMP 660, and AMP 1043) and two bioactive compounds (disodium ethylenediaminetetraacetic acid [EDTA] and glycerol monolaurate) was assessed against a range of 35 mastitis-causing pathogens.
Pathogens
October 2024
One Health Unit, Department of Biomedical, Surgical and Dental Sciences, School of Medicine, University of Milan, Via Pascal 36, 20133 Milan, Italy.
Economic, social, and environmental sustainability are the results of efforts aiming to improve all aspects of milk production, respecting animal welfare and improving herd health. An epidemiological study was designed to assess the role of contagious pathogens ( and ) in a cohort of 120 dairy herds located in the southern regions of Italy. Milk quality was assessed using certified methods, and the prevalence of mastitis pathogens in bulk tank milk was determined using quantitative polymerase chain reaction.
View Article and Find Full Text PDFAnimals (Basel)
September 2024
College of Science and Technology, Gansu Agriculture University, Lanzhou 730070, China.
is a highly contagious Gram-positive bacterium that causes mastitis, has a high infectivity for mammary epithelial cells, and becomes challenging to treat. However, the molecular interactions between it and mammary epithelial cells remain poorly understood. This study analyzed differential gene expression in mammary epithelial cells with varying levels of infection using UID-Dual transcriptome sequencing and bioinformatics tools.
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