A Laplace pressure based microfluidic trap for passive droplet trapping and controlled release.

Biomicrofluidics

Department of Biomedical Engineering, University of California, Irvine, 3201 Natural Sciences II, Irvine, California 92697, USA.

Published: March 2012

Here, we present a microfluidic droplet trap that takes advantage of the net Laplace pressure force generated when a droplet is differentially constricted. Mathematical simulations were first used to understand the working range of the component; followed by finite element modeling using the CFD software package to further characterize the behavior of the system. Controlled release of the trapped droplets is also demonstrated through both a mechanical method and a chemical method that manipulates the total pressure exerted on the trapped droplet. The unique design of this trapping device also provides the capability for selection of a single droplet from a train, as well as droplet fusion.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365347PMC
http://dx.doi.org/10.1063/1.3687400DOI Listing

Publication Analysis

Top Keywords

laplace pressure
8
controlled release
8
droplet
6
pressure based
4
based microfluidic
4
microfluidic trap
4
trap passive
4
passive droplet
4
droplet trapping
4
trapping controlled
4

Similar Publications

Electroosmosis and surcharge preloading represent two effective soil consolidation methodologies. Their combined application has been proven to be effective in shortening the consolidation period and mitigating the degradation of electroosmotic consolidation performance due to crack generation. In this study, an axisymmetric free-strain consolidation analytical model incorporating a continuous drainage top boundary was established.

View Article and Find Full Text PDF

Biomimetic high-efficiency fog collector based on fractal spiral structure.

J Colloid Interface Sci

December 2024

Ministry of Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei University, Wuhan 430062, People's Republic of China; State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, People's Republic of China. Electronic address:

Fog collection provides a promising solution to the freshwater shortage. However, the efficiency of conventional fog collection apparatus is significantly reduced under the complex and variable natural conditions. Furthermore, fog collectors are usually plagued by intricate designs and inadequate durability, resulting in degradation of their structural and surface integrity over time.

View Article and Find Full Text PDF

Hydrogel-based nonwoven with persistent porosity for whole-stage hypertonic wound healing by regulating of water vaporization enthalpy.

Biomaterials

May 2025

State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, 2999 North Renmin Road, Shanghai, 201620, China.

Moisture induced by wound exudate is crucial throughout the wound repair process. The dressing directly affects the absorption, permeation, and evaporation of the wound exudate. However, most dressings in clinical often result in excessive dryness or moisture of wound due to their monotonous structure and function, leading to ineffective thermodynamic control of evaporation enthalpy.

View Article and Find Full Text PDF

The ability of a surface to completely absorb a liquid droplet is an important property that can be controlled by geometrical structure and chemical composition of the surface. Here, using Laplace pressure and Gibbs free energy (GFE) considerations, a capped truncated microcone array geometry is proposed to obtain a near zero degree for contact angle (θ) of a water droplet. Our results showed that two essential conditions must be met to achieve a superabsorbent surface.

View Article and Find Full Text PDF

Radius of investigation (ROI) is of great significance in well testing and reserve estimation. The studies on ROI over the past decades were mainly focusing on homogeneous reservoirs. In heterogeneous formations, such as composite reservoirs and fractured reservoirs, the problem remains unsolved.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!