Osteonecrosis of the femoral head: An update in year 2012.

World J Orthop

Anjan P Kaushik, Anusuya Das, Quanjun Cui, Department of Orthopaedic Surgery, University of Virginia, Charlottesville, VA 22903, United States.

Published: May 2012

Osteonecrosis is a phenomenon involving disruption to the vascular supply to the femoral head, resulting in articular surface collapse and eventual osteoarthritis. Although alcoholism, steroid use, and hip trauma remain the most common causes, several other etiologies for osteonecrosis have been identified. Basic science research utilizing animal models and stem cell applications continue to further elucidate the pathophysiology of osteonecrosis and promise novel treatment options in the future. Clinical studies evaluating modern joint-sparing procedures have demonstrated significant improvements in outcomes, but hip arthroplasty is still the most common procedure performed in these affected younger adults. Further advances in joint-preserving procedures are required and will be widely studied in the coming decade.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364317PMC
http://dx.doi.org/10.5312/wjo.v3.i5.49DOI Listing

Publication Analysis

Top Keywords

femoral head
8
osteonecrosis
4
osteonecrosis femoral
4
head update
4
update year
4
year 2012
4
2012 osteonecrosis
4
osteonecrosis phenomenon
4
phenomenon involving
4
involving disruption
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!