Familial adenomatous polyposis (FAP) is the commonest form of inherited form of CRC. It comprises of about 5% of all the colorectal cancers (CRCs). FAP patients have a family history of CRC that suggests a genetic contribution, common exposures among family members, or a combination of both. This case report gives a glimpse of the phenotypic manifestation of FAP and the underlying molecular mechanism which leads to FAP, in addition it also sheds a light on the management of FAP in early stages of life.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087069 | PMC |
| http://dx.doi.org/10.1007/s12262-010-0229-7 | DOI Listing |
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