Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
An open-source, user-friendly, machine-learning method for automated segmentation and analysis of peripheral nerve cross-sections.
Plast Reconstr Surg
January 2025
Division of Plastic Surgery, Mayo Clinic; Rochester, MN.
Introduction: Quantitative neuromorphometry analysis of the peripheral nerve is paramount to nerve regeneration research. However, this technique relies upon accurate segmentation and determination of myelin and axonal area. Manual histological analysis methods are time- consuming, and subject to error and bias.
View Article and Find Full Text PDFPolydatin retards the progression of osteoarthritis by maintaining bone metabolicbalance and inhibiting macrophage polarization.
Front Bioeng Biotechnol
January 2025
The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Background: Polydatin (PD), also known as tiger cane glycoside, is a natural compound extracted from the Japanese knotweed plant, which is often referred to as white resveratrol. It exhibits anti-inflammatory, antioxidant, and anti-apoptotic effects in the treatment of various diseases. However, the potential molecular mechanisms of PD in osteoarthritis have not been clearly elucidated.
View Article and Find Full Text PDFMetabolism and effects of acetoaceto--toluidine in the urinary bladder of humanized-liver mice.
J Toxicol Pathol
January 2025
Department of Molecular Pathology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, Japan.
Occupational exposure to aromatic amines is a major risk factor for urinary bladder cancer. Our previous studies showed that acetoaceto--toluidine, which is produced using -toluidine as a raw material, promotes urinary bladder carcinogenesis in rats. We also found high concentrations of -toluidine, a human bladder carcinogen, in the urine of acetoaceto--toluidine-treated rats, indicating that urinary -toluidine derived from acetoaceto--toluidine may play an important role in bladder carcinogenesis.
View Article and Find Full Text PDFA Literature Review on Oral Lumenoscopy: A Non-invasive Method for Diagnosing Oral Potentially Malignant Disorders.
Cureus
December 2024
Oral Medicine and Radiology, SRM Kattankulathur Dental College and Hospital, SRM Institute of Science and Technology (SRMIST), Chennai, IND.
Dentistry still faces difficulties in diagnosing oral precancer and cancer, especially when it comes to early phase changes or disease detection, evaluation, and treatment. In essence, oral lumenography is the process of identifying oral lesions using a chemiluminescent light source and a toluidine blue labeling system. Since neoplastic epithelial cells have a changed nuclear-cytoplasmic ratio, acetic acid dehydration brings out this nuclear density and gives the tissue an "acetowhite" look.
View Article and Find Full Text PDFAutomated xeno-free chondrogenic differentiation from human embryonic stem cells: Enhancing efficiency and ensuring high-quality mass production.
Regen Ther
June 2024
Center for Regenerative Medicine, National Center for Child Health and Development Research Institute, Tokyo, Japan.
Introduction: Repairing damaged cartilage poses significant challenges, particularly in cases of congenital cartilage defects such as microtia or congenital tracheal stenosis, or as a consequence of traumatic injury, as the regenerative potential of cartilage is inherently limited. Stem cell therapy and tissue engineering offer promising approaches to overcome these limitations in cartilage healing. However, the challenge lies in the size of cartilage-containing organs, which necessitates a large quantity of cells to fill the damaged areas.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!