AI Article Synopsis

  • - The study compared the effectiveness of surgical cryoablation (SCA) and percutaneous cryoablation (PCA) for treating renal tumors by analyzing the outcomes of 194 patients over a follow-up period.
  • - Both treatment methods yielded similar rates of overall survival (OS), cancer-specific survival (CSS), and recurrence-free survival (RFS), with five-year rates showing slight variations but no significant differences between the two approaches.
  • - PCA resulted in a much shorter hospital stay (0.7 days) compared to SCA (3.2 days), indicating it may be a more convenient option for patients while still offering effective treatment.

Article Abstract

Purpose: To compare outcomes between patients undergoing surgical and percutaneous cryoablation for treatment of renal masses and identify prognostic variables that determine survival.

Patients And Methods: We retrospectively evaluated the medical records of 194 patients who underwent cryoablation for renal tumors between 1997 and 2008 at a single large center. Patient demographics, tumor characteristics, perioperative data, and follow-up details were recorded. Univariate and multivariate Cox proportional hazards analysis was performed to identify predictors of overall (OS), cancer-specific (CSS), and recurrence-free survival (RFS).

Results: Cryoablation was performed percutaneously (PCA) in 141 patients for 154 tumors, while 53 patients were treated surgically (SCA) using an open or laparoscopic approach for 54 tumors. Mean follow-up was 44.5 months in SCA and 36.1 months in PCA. PCA had a shorter duration of hospital stay (0.7 days vs 3.2 days, P<0.0001). The rate of residual (P=0.38) and recurrent disease (P=0.18) was not significantly different between the two groups. Five-year OS, CSS, and RFS were 78.81%, 100%, and 85.23% for SCA, and 77.71%, 98%, and 95.56% for PCA, respectively; the type of approach was not predictive of OS, CSS, and RFS.

Conclusions: SCA and PCA both provide adequate oncologic control for renal masses. Duration of hospital stay was lower in patients undergoing PCA.

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Source
http://dx.doi.org/10.1089/end.2012.0244DOI Listing

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