Background: In Iran, the number of stray dogs in cities and villages necessitates epidemiologic investigations. This study has undertaken an epidemiologic survey in Ilam, Iran with regard to animal bites during 1999-2009.
Methods: This was a cross-sectional descriptive study. The data due to animal bites was collected from patients and analyzed.
Results: The number of animal bites reported was 4420, which included 3032 men (68.3%) and 398 women (31.7%). Most animal bites were reported in the 10-19 year-old (1172, 26%) age group. The feet were the most commonly attacked body part, which was reported in 3177 cases (71.8%). Most bites were from dogs (3942 cases, 89.15%). Of cases, 3419 (77.3%) resided in rural areas while 1001 (22.7%) were urban residents. The number of patients with incomplete vaccinations was 3596 (81.3%) compared to 824 (18.7%) completely vaccinated patients.
Conclusion: The present study showed a high incidence of animal bites in Ilam, which necessitates the importance of rabies prevention and control. It is recommended that the sanitation authorities provide for and implement measures to determine beneficial ways to avoid and control rabies infection in this part of Iran.
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Toxins (Basel)
December 2024
Molecular Toxinology Lab, Research and Development Department, Ezequiel Dias Foundation-FUNED, Belo Horizonte 30510-010, MG, Brazil.
Spiders of the genus represent a public health problem in Brazil due to the severity of the cutaneous and systemic effects that may result from their bite. In the systemic form of loxoscelism, hemolytic anemia, thrombocytopenia, and disseminated intravascular coagulation can occur. Despite the seriousness of accidents, the venom of some species has not yet been properly characterized considering these hemotoxic effects, such as that of , , and .
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December 2024
Poison Control Center, The University of Arizona College of Pharmacy, Tucson, AZ 85724, USA.
The onset, progression, and severity of pain following rattlesnake envenomation are highly variable between patients. Pain can be severe and persistent, seemingly refractory to opioid analgesics. The ability of antivenom to directly relieve pain has not been well studied.
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December 2024
School of Biotechnology, Amrita Vishwa Vidyapeetham, Kollam 690 525, Kerala, India.
The intricate combination of organic and inorganic compounds found in snake venom includes proteins, peptides, lipids, carbohydrates, nucleotides, and metal ions. These components work together to immobilise and consume prey through processes such as paralysis and hypotension. Proteins, both enzymatic and non-enzymatic, form the primary components of the venom.
View Article and Find Full Text PDFDiscov Med
December 2024
Emergency Department, Affiliated Hospital of Zunyi Medical University, 563000 Zunyi, Guizhou, China.
Background: To explore the mechanism of hyperbaric oxygen (HBO) intervention on acute lung injury secondary to snake venom poisoning and provide more toxicological and clinical evidence for venom poisoning.
Methods: Male Kunming mice (n = 96) were randomly divided into four groups: the control group which was not given any interventional treatments, venom group in which each mouse was injected with venom (1 mg/kg) through the tail vein, antivenom group in which each mouse was injected with anti- venom immediately after the model was successfully established, and HBO+antivenom group in which each mouse was given HBO treatment at 1 h, 5 h, 11 h and 23 h following the injection of antivenom. Lung tissues of mice were obtained and processed for the detection of the lung coefficient, the levels of inflammatory factors such as interleukin (IL)-6, IL-10 and IL-17, and the protein expression of retinoic acid receptor (RAR)-related orphan receptor gamma (RORγt) and forkhead box P3 (FOXP3).
Pharmacol Biochem Behav
December 2024
Programa de Pós-Graduação em Farmacologia, Universidade Federal de Santa Maria, RS, Brazil. Electronic address:
Schizophrenia is a mental disorder characterized by positive, negative, and cognitive symptoms which is treated with antipsychotics. However, these drugs present several side effects and, some schizophrenia symptoms, like cognitive, are difficult to treat. The peroxisome proliferator-activated receptors-gamma (PPAR-γ) are expressed in dopaminergic neurons of the midbrain participating in the modulation of neurotransmitters release like dopamine.
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