Cocaine use during pregnancy and health outcome after 10 years.

Drug Alcohol Depend

Case Western Reserve University, Mandel School of Applied Social Sciences, 11235 Bellflower Road, Cleveland, OH 44106, USA.

Published: November 2012

Background: Women who used cocaine during pregnancy may become at risk for increased physical and mental health problems.

Methods: Three hundred and twenty-one (158 cocaine use during pregnancy (PC), 163 no cocaine (NC)) women were assessed using the Health Survey Questionnaire (SF-36V2) 10 years after infant birth. Factors related to mental and physical health, and co-occurring with PC, were evaluated using multiple regression.

Results: Controlling for age and education, PC women reported poorer total perceived mental health (PMH) (46.3±.9 vs. 50.7±.9, p<.001), more bodily pain (48.1±1.0 vs. 51.5±1.0, p<.02) and poorer health perceptions (46.8±.9 vs. 49.7±.9, p<.03) than NC women. PC women had lower BMI (29% vs. 32%, p<.006), higher current alcoholic drinks per/week (4.05±15.5 vs. 1.29±3.51, p<.005) and number of cigarettes per day (9±10.6 vs. 4±6.5, p<.0001) and greater total life strain (Family Inventory of Life Events and Changes (FILE)) (4.6±4.9 vs. 3.2±3.2, p<.004) than NC women. Regression analyses indicated that body mass index (BMI) mediated the effect of prior cocaine use on perceived physical health (PPH) and total life strain had additive effects. Current cigarette use and total life stress partially mediated the effects of cocaine use on PMH and also had additive independent effects.

Conclusions: PC use is a marker for poor health after 10 years. Mediators of these relationships (BMI, stressful life events and current tobacco use) should be considered when designing interventions to promote health.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595593PMC
http://dx.doi.org/10.1016/j.drugalcdep.2012.04.015DOI Listing

Publication Analysis

Top Keywords

cocaine pregnancy
12
mental health
8
health
5
cocaine
4
pregnancy health
4
health outcome
4
outcome years
4
years background
4
background women
4
women cocaine
4

Similar Publications

Prenatal syphilis and adverse pregnancy outcomes in women with HIV receiving ART in Brazil: a population-based study.

Lancet Reg Health Am

November 2024

Ministry of Health - Brazil, Department of Surveillance, Prevention and Control of STIs, AIDS, and Viral Hepatitis, SRTVN Quadra 701, Lote D, Edifício PO700 - 5º Andar, CEP: 70719-040, Brasília/DF, Brazil.

Background: We aimed to examine factors associated with prenatal syphilis, including prenatal care, and pregnancy outcomes of pregnant women with HIV in Brazil.

Methods: Retrospective data were gathered from a national cohort of Brazilian women with HIV on antiretroviral therapy who became pregnant between January 2015 and May 2018. Prenatal syphilis was defined by clinical diagnoses with treatment or any positive syphilis laboratory result between 30 days before conception and pregnancy conclusion.

View Article and Find Full Text PDF

Patterns of Maternal Single and Polysubstance Use in the US: A Latent Class Analysis.

J Stud Alcohol Drugs

January 2025

Department of Population Health Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States.

Objective: Substance use patterns vary considerably in the general population, yet little is known about patterns before and during pregnancy. The purpose of this study was to describe single substance and polysubstance use (PSU) before and during pregnancy among recent births in the United States (US) and compare exposure patterns.

Methods: We used data from the Pregnancy and Risk Assessment Monitoring System (PRAMS) postpartum survey for 2016-2018 to estimate the prevalence and identify patterns of substance use by participants one to three months before and during pregnancy.

View Article and Find Full Text PDF

Background: The aim of this study was to determine whether orexigenic neuropeptides, orexin and galanin, and anorexigenic neuropeptides, alpha-melanocyte-stimulating hormone (α-MSH) and cocaine- and amphetamine-regulated transcript (CART), are implicated in hyperemesis gravidarum (HG).

Methods: Fifty pregnant women who had been diagnosed with HG between April 2022 and February 2023 at the Siirt University Faculty of Medicine Training and Research Hospital (tertiary center) were recruited for this study. An equal number of pregnant women without an HG diagnosis were included in the study as the control group.

View Article and Find Full Text PDF
Article Synopsis
  • Researchers need to find out what factors might put babies at risk of being taken out of their homes, especially due to their parents' substance use.
  • In a study with 1,808 parent-baby pairs, most of the parents were Non-Hispanic White, and many babies were exposed to drugs like alcohol and opioids before birth.
  • The study found that many babies with drug exposure didn't get to go home with their parents, and understanding how substance use affects placement decisions can help improve support for families in need.
View Article and Find Full Text PDF

Prenatal and postnatal cocaine exposure enhances the anxiety- and depressive-like behaviors in rats: An ontogenetic study.

Int J Dev Neurosci

October 2024

Subdirección de Investigaciones Clínicas, Laboratorio de Neurofarmacología Conductual, Microcirugía y Terapéutica Experimental, Instituto Nacional de Psiquiatría, Mexico City, Mexico.

Article Synopsis
  • * Cocaine was administered to pregnant rats, and their male offspring were later tested for anxiety and depressive behaviors at 30, 60, 90, and 120 days old.
  • * Results showed that the negative effects of cocaine exposure on mood-related behaviors increased with age, being most pronounced in older adult rats.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!