Tumor archaeology reveals that mutations love company.

Cell

Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

Published: May 2012

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2012.05.010DOI Listing

Publication Analysis

Top Keywords

tumor archaeology
4
archaeology reveals
4
reveals mutations
4
mutations love
4
love company
4
tumor
1
reveals
1
mutations
1
love
1
company
1

Similar Publications

The potential of ancient DNA analyses to provide independent sources of information about events in the historical record remains to be demonstrated. Here we apply palaeogenomic analysis to human remains excavated from a medieval well at the ruins of Sverresborg Castle in central Norway. In , the Old Norse of King Sverre Sigurdsson, one passage details a 1197-CE raid on the castle and mentions a dead man thrown into the well.

View Article and Find Full Text PDF

The Flood is the first pictorial scene that Michelangelo Buonarroti painted on the ceiling of the Sistine Chapel in the Vatican. On the right side of the fresco a woman with abnormal breast morphology is presented and the nature of her disease is considered using the Guidelines for Iconodiagnosis. A team of experts covering art history, art expertise, medicine, genetics, and pathology undertook the process and concluded that the pathology shown is probably breast cancer, most likely linked to the symbolic significance of an inevitable death as expressed in the Book of Genesis.

View Article and Find Full Text PDF

Archaeological studies of pre-historic Arctic cultures are often limited to artefacts and architecture; such records may be incomplete and often do not provide a continuous record of past occupation. Here, we used lake sediment archives to supplement archaeological evidence to explore the history of Thule and Dorset populations on Somerset Island, Nunavut (Canada). We examined biomarkers in dated sediment cores from two ponds adjacent to abandoned Thule settlements (PaJs-3 and PaJs-13) and compared these to sediment cores from two ponds without past human occupation.

View Article and Find Full Text PDF

Case report: Boundaries of oncological and traumatological medical care in ancient Egypt: new palaeopathological insights from two human skulls.

Front Med (Lausanne)

May 2024

Department of History (Prehistory Unit), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.

The present case studies report malignant neoplastic and traumatic lesions observed on two ancient Egyptian skulls held at the Duckworth Collection (Cambridge University). The analysis aims to characterise the lesions and provide a diagnosis using a methodology based on micro-CT scanning and microscopic bone surface analysis. Results pointed towards neoplastic lesions in both cases and healed severe skull trauma in one of them suggesting successful traumatological therapy.

View Article and Find Full Text PDF

A case of Multiple Myeloma from 19 century North America: Aligning the clinical and archaeological records.

Anthropol Anz

August 2024

Human Osteology Lab, Department of Earth & Environmental Systems, Indiana State University, Terre Haute, IN, 47809 USA.

The first archaeological case of multiple myeloma (MM) from historic period North America is presented. Only 49 cases of MM have been reported from archaeological contexts and recent reviews have alternately rejected either 24 of the cases or all 49 cases and found them all to more likely be cases of metastatic carcinoma (MC). The trend in the debate over the interpretation of these cancers is that MC is an ancient disease while MM is likely a disease of modernity.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!