Objectives/hypothesis: We report the first case of laryngeal stenosis with granuloma in a patient with severe congenital neutropenia (SCN).

Study Design: Case report and retrospective review.

Methods: Review of medical records.

Results: A 6-year-old female who was diagnosed with SCN presented with a cough and wheezing. An endoscopic study revealed laryngeal stenosis with granuloma. Tracheotomy and direct laryngoscopy were performed under general anesthesia, and administration of granulocyte colony-stimulating factor was started. The laryngeal granuloma disappeared 3 weeks later, and the tracheal stoma was closed.

Conclusions: Presence of a laryngeal lesion should be considered in SCN patients with persistent airway symptoms.

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http://dx.doi.org/10.1002/lary.23375DOI Listing

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