The dissociation constant (K) of various molecular interactions was determined using a novel competition assay with binding magnetic relaxation nanosensors (bMRs). In this assay, changes in the magnetic relaxation of an aqueous suspension of the nanosensors facilitate the fast determination of K values using nanomolar protein concentrations.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461998 | PMC |
http://dx.doi.org/10.1002/anie.201202077 | DOI Listing |
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