Keratocystic odontogenic tumor is characterized by high recurrence rates. Conservative or aggressive management has been suggested as a method of treatment. Decompression is a conservative treatment that has been used in the treatment of large odontogenic cysts. The authors report a case of a 14-year-old patient with a keratocystic odontogenic tumor located in the right maxilla, which was treated by decompression followed by enucleation with curettage. The lesion did not recur on follow-up for 3 years after the enucleation surgery.
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http://dx.doi.org/10.1097/SCS.0b013e31824de43f | DOI Listing |
Natl J Maxillofac Surg
November 2024
Kasturba Medical College, Manipal, Karnataka, India.
Special care is required for the management of jaw lesions in pediatric population. The following article describes the decompression technique as the least aggressive approach for the management of pediatric mandibular odontogenic keratocyst. A custom-made acrylic splint was fabricated around teeth, and it was attached to a piece of Foley's catheter to be used as a decompression port.
View Article and Find Full Text PDFJ Clin Exp Dent
December 2024
Department of Oral Surgery and Oral Medicine, Faculty of Dentistry, Srinakharinwirot University.
Background: N6-methyladenosine (m6A), the most abundant internal RNA modification in mammals, plays a critical role in many forms of cancer. Methyltransferase-like 3 (METTL3) serves as the main catalytic subunit of the m6A writer and plays a role in the progression of head and neck squamous cell carcinoma. To date, the role of METTL3 in odontogenic lesions has never been investigated.
View Article and Find Full Text PDFJ Craniofac Surg
January 2025
Department of Oral, Plastic, and Aesthetic Surgery, Hospital of Stomatology, Jilin University, Changchun, Jilin, China.
Odontogenic keratocysts (OKCs) are an invasive type of odontogenic cyst that rarely occurs in the maxilla. This article presents a case of OKC complicated with ectopic teeth occurring in the maxillary sinus. This article collects a case of a 19-year-old female patient with an ectopic tooth in the maxillary sinus associated with an OKC.
View Article and Find Full Text PDFJ Clin Med
December 2024
Department of Oral and Maxillofacial Diagnostic Sciences, College of Dentistry, Taibah University, Medina 41477, Saudi Arabia.
To determine the prevalence of oral and maxillofacial lesions among patients at King Abdulaziz University from January 2016 to December 2022. : This cross-sectional observational study included patients diagnosed with oral and maxillofacial intra-bony lesions based on radiological findings and confirmed by histopathological examination. The lesions were classified according to the fourth edition of the World Health Organization Classification of Head and Neck Tumors.
View Article and Find Full Text PDFDiagn Pathol
January 2025
Cell Culture Laboratory, School of Dentistry, Federal University of Para, Rua Augusto Correa, 01 Guama, Belem, PA, 66075110, Brazil.
Background: Considering the significant participation of the microenvironment in the local aggressiveness of odontogenic keratocysts, this study aims to evaluate the expression of ADAMTS-1 and its substrates, versican, aggrecan and brevican in this locally invasive odontogenic cyst.
Methods: Immunohistochemistry and polymerase chain reaction (PCR) were conducted on 30 cases of odontogenic keratocysts (OKCs) and 20 dental follicles (DFs).
Results: The immunohistochemical expression of these proteins was predominantly cytoplasmic and granular across all samples.
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