Background: Evaluation of the efficacy of a novel medical device for removal of retained intrauterine devices (IUDs) under direct vision without uterine distention is reported.
Cases: The five cases presented used the novel medical device to remove the IUDs. One woman had an incarcerated IUD, two women had fractured IUDs and two women had IUDs with lost threads. All IUDs were removed completely with use of direct vision without uterine distention.
Conclusions: The device is effective for the removal of incarceration IUDs under direct vision without uterine distention.
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http://dx.doi.org/10.1016/j.contraception.2012.04.002 | DOI Listing |
ALTEX
January 2025
National Institutes of Health, National Institute for Environmental Health Sciences, DTT/NICEATM, Durham, NC, USA.
The integration of artificial intelligence (AI) into new approach methods (NAMs) for toxicology rep-resents a paradigm shift in chemical safety assessment. Harnessing AI appropriately has enormous potential to streamline validation efforts. This review explores the challenges, opportunities, and future directions for validating AI-based NAMs, highlighting their transformative potential while acknowledging the complexities involved in their implementation and acceptance.
View Article and Find Full Text PDFCurr Biol
January 2025
Department of Psychology, New York University, New York, NY 10003, USA; Center for Neural Science, New York University, New York, NY 10003, USA. Electronic address:
In human adults, visual perception varies throughout the visual field. Performance decreases with eccentricity and varies around polar angle. At isoeccentric locations, performance is typically higher along the horizontal than vertical meridian (horizontal-vertical asymmetry [HVA]) and along the lower than the upper vertical meridian (vertical meridian asymmetry [VMA]).
View Article and Find Full Text PDFAtten Percept Psychophys
January 2025
Department of Psychology, Huron University College at Western: London, 1349 Western Road, London, ON, N6G 1H3, Canada.
Previous studies have reported visual motion aftereffects (MAEs) following prolonged exposure to auditory stimuli depicting motion, such as ascending or descending musical scales. The role of attention in modulating these cross-modal MAEs, however, remains unclear. The present study manipulated the level of attention directed to musical scales depicting motion and assessed subsequent changes in MAE strength.
View Article and Find Full Text PDFHandb Exp Pharmacol
January 2025
Genentech Inc, South San Francisco, CA, USA.
In this chapter, we envision the future of Quantitative Systems Pharmacology (QSP) which integrates closely with emerging data and technologies including advanced analytics, novel experimental technologies, and diverse and larger datasets. Machine learning (ML) and Artificial Intelligence (AI) will increasingly help QSP modelers to find, prepare, integrate, and exploit larger and diverse datasets, as well as build, parameterize, and simulate models. We picture QSP models being applied during all stages of drug discovery and development: During the discovery stages, QSP models predict the early human experience of in silico compounds created by generative AI.
View Article and Find Full Text PDFCureus
December 2024
Optics and Optometry Division, Investigative Techniques in Optometry Research Group, Department of Biomedical Sciences, University of West Attica, Athens, GRC.
Diabetic retinopathy (DR) is a leading cause of vision impairment and blindness globally, particularly among working-age adults. As the prevalence of diabetes continues to rise, understanding factors that influence DR development and progression is increasingly important. Recent studies suggest a protective association between a longer axial length (AL) of the eye and the risk of DR, particularly in myopic individuals.
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