[The alteration of threshold of clinical decision making in connection with the implementation of direct detection of cholesterol-low density lipoproteins in laboratory practice].

The retrospective study included 494 patients (the triglycerides level was less than 4.2 mole per liter) examined during January-March 2010 in four medical institutions of Volgograd and Voljsky. The comparative analysis was made of results of the Friedewald equation test and direct test of cholesterol-low density lipoproteins in the same samples. The correlation between the results of different tests of cholesterol-low density lipoproteins was low (R2=0.65). The labeling of patients as particular category according the results of testing of cholesterol-low density lipoproteins with different techniques matched only in 55% of cases. At the same time, under direct testing of cholesterol-low density lipoproteins in 40% of cases the patients were labeled as low risk category.