Background: Pneumothorax has traditionally been treated in the Emergency Department by tube thoracostomy. However, this is an invasive procedure with high risk of complication and prolonged hospitalization.
Discussion: In select settings, there are alternative forms of management of pneumothorax that carry lower risks and may reduce hospital stay. This article reviews the settings in which less invasive treatment, including observation alone, may be indicated. This article also reviews the techniques for simple aspiration and small-bore catheter insertion (by either Seldinger or catheter-over-wire technique) with Heimlich valve, as well as the indications, contraindications, and potential risks and benefits of each.
Conclusions: The practices of observation, simple aspiration, and small-bore catheter insertion with Heimlich valve for selected patients may decrease complications, time, and costs by avoiding invasive procedures and hospital admissions.
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http://dx.doi.org/10.1016/j.jemermed.2012.02.049 | DOI Listing |
Pharm Dev Technol
January 2025
Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Alexandria University, Egypt.
Tear trough deformity (TTD) is a significant cosmetic concern, with current treatments relying primarily on invasive injectable fillers, which are costly and carry risks of complications. Despite the widespread use of hyaluronic acid (HA) in cosmetic applications, its poor dermal permeation has limited the development of effective topical fillers for TTD.This study aim to develop and evaluate a novel hyaluronic acid nanogel (nanofiller, NF) as a non-invasive topical filler for TTD.
View Article and Find Full Text PDFActa Cardiol
January 2025
Department of Cardiology, China Aerospace Science & Industry Corporation 731 Hospital, Beijing, China.
Background: Previous studies have shown that valvular heart disease (VHD) is closely related to the development of heart-related disease (HRD). However, the current research for the relationship between VHD and HRD is complex and poorly targeted. Meanwhile, these studies lack the support of bibliometric analysis results.
View Article and Find Full Text PDFLaetrile, known as vitamin B17, is often used interchangeably with amygdalin. Laetrile is a semi-synthesis product of amygdalin, whereas amygdalin is a naturally occurring substance in many plants. Both compounds have a nitrile functional group that, when activated by the intestinal enzyme β-glucosidases, releases hydrogen cyanide.
View Article and Find Full Text PDFTransfus Med
January 2025
SUWON (Surgery, Oncology and Womens), Department of Haematology, University of Oxford, Oxford, UK.
Iron deficiency anaemia (IDA) poses a significant health challenge during pregnancy, affecting up to 30% of pregnant women in the UK. It has been linked to poor health outcomes for the mother, foetus, and the infant. Despite its prevalence and impact, current diagnostic and therapeutic approaches are limited.
View Article and Find Full Text PDFDis Model Mech
January 2025
Department of Microbiology, Trinity College, Dublin D02 VF25, Ireland.
Gestational trophoblastic disease (GTD) describes a group of rare benign and cancerous lesions originating from the trophoblast cells of the placenta. These neoplasms are unconventional entities, being one of the few instances in which cancer develops from the cells of another organism, the foetus. Although this condition was first described over 100 years ago, the specific genetic and non-genetic drivers of this disease remain unknown to this day.
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