This cross-sectional study assessed the association between health-promoting lifestyle and depression in metabolic syndrome patients by using a questionnaire survey in Korea. Data were collected from 195 adults (> 20 years old) with hypertension, dyslipidemia and diabetes. The correlation coefficient (r) between health-promoting lifestyle and depression was -0.309 (P < 0.001), and correlation between individual lifestyle dimensions and depression varied from -0.135 to -0.391. The non-depressed group had higher health-promoting lifestyle scores than the depressed group (P = 0.003). Scores for three dimensions of the health-promoting lifestyle profile--self-actualization (P < 0.001), interpersonal support (P = 0.001) and stress management (P = 0.025)--were significantly higher in the non-depressed groups. Logistic regression analysis provided an odds ratio of 2.766 (P = 0.003) for health-promoting lifestyle between the two groups. For patients with metabolic syndrome, depression was negatively associated with health-promoting lifestyle and is an important factor affecting health-promoting behaviour.
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