Introduction: Osseous metaplasia in the gastrointestinal tract is a rare phenomenon.
Case Presentation: We present the case of a 62-year-old Hispanic man with two colonic polypoid lesions, one of which, upon resection and histopathological examination, was found to be a traditional serrated adenoma with a focus of stromal osseous metaplasia.
Conclusions: Our patient's case is the third report of stromal osseous metaplasia in a traditional serrated adenoma of the sigmoid colon.
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http://dx.doi.org/10.1186/1752-1947-6-133 | DOI Listing |
Clin Transl Oncol
January 2025
Hereditary Cancer Unit, Medical Oncology Department, Puerta de Hierro University Hospital, Majadahonda, 28222, Madrid, Spain.
Hereditary polyposis syndromes are significant contributors to colorectal cancer (CRC). These syndromes are characterized by the development of various types and numbers of polyps, distinct inheritance patterns, and extracolonic manifestations. This review explores these syndromes with a focus on their genetic characteristics.
View Article and Find Full Text PDFJ Clin Pathol
January 2025
Harvard Medical School, Boston, Massachusetts, USA
Aims: WNT signalling pathway dysregulation is often a critical early component in colorectal neoplasia, particularly the chromosomal instability pathway. Using two WNT reporters, and , we sought to assess whether these polyps demonstrate predictable expression patterns and if these patterns show diagnostic value.
Methods: We evaluated 23 adenomas (TA), 23 sessile serrated lesions (SSLs), 14 SSL with dysplasia and 38 traditional serrated adenomas (TSA).
PLoS One
December 2024
Sinosteel Maanshan General Institute of Mining Research CO.,Ltd., Maanshan, China.
Hard structural planes mainly exist in rock slopes and their creep characteristics largely determine slope stability. Traditional models have some shortcomings in describing the creep characteristics of hard structural planes, such as poor adaptability and unclear physical meaning of parameters. In order to overcome these shortcomings, based on the creep failure mechanism of hard structural planes, an element combination model is adopted in the study.
View Article and Find Full Text PDFCureus
October 2024
Gastroenterology, Faculdade de Medicina, Universidade de Sao Paulo, Serviço de Endoscopia Gastrointestinal do Hospital das Clínicas, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP), São Paulo, BRA.
Traditional serrated adenomas (TSAs) of the duodenum are rare lesions with potential for malignant transformation. We present the case of a 44-year-old female with a history of bariatric surgery who presented with worsening abdominal pain, nausea, and significant weight loss. Imaging studies, including MRI, revealed a 3.
View Article and Find Full Text PDFGastrointest Endosc
October 2024
Department of Gastroenterology and Hepatology, Gunma University Graduate School of Medicine, Maebashi, Japan.
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