Premise Of The Study: Using genomic shotgun 454 sequencing, 50 candidate microsatellite markers were targeted for the arctic-alpine polyploid perennial herb Bistorta vivipara to distinguish between individual genets and ramets within a population.
Methods And Results: Out of the 50 markers, 31 were polymorphic for seven test samples. We have developed a multiplex protocol for 16 of these microsatellite markers.
Conclusions: Our results show that the microsatellite markers provide a powerful tool for the research on genetic variation of B. vivipara.
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http://dx.doi.org/10.3732/ajb.1100504 | DOI Listing |
Cureus
December 2024
Medicine, Army Medical College, Rawalpindi, PAK.
The role of p53 expression in colorectal cancer (CRC) was investigated in this immunohistochemical analysis of 110 CRC patients. The study aimed to explore the relationship between p53 expression and clinicopathological features, such as tumor grade, size, lymph node involvement, and molecular subtypes. The mean age of patients was 52.
View Article and Find Full Text PDFInt J Colorectal Dis
January 2025
Internal Medicine, Jilin Cancer Hospital, Changchun, China.
Purpose: This phase II study is designed to evaluate the combination therapy involving suvemcitug and envafolimab with FOLFIRI in microsatellite-stable or mismatch repair-proficient (MSS/pMMR) colorectal cancer (CRC) in the second-line treatment setting.
Methods: This study is a non-randomized, open-label prospective study comprising multiple cohorts (NCT05148195). Here, we only report the data from the CRC cohort.
The white prunicola scale (Maskell) is an important pest of fruit and ornamental plants, characterised by its wide distribution, broad host range and distinct biological traits. In this study, a comprehensive population genetic analysis of in China was conducted, focusing on genetic diversity, genetic structure, relationships among geographical populations, and population dynamics. Microsatellite molecular and mitochondrial COI markers were used to examine the genetic diversity and structure of 19 populations across 10 provinces in China.
View Article and Find Full Text PDFParasit Vectors
January 2025
Department of Genetics and Evolutionary Biology. Institute of Biosciences, University of São Paulo, Rua Do Matão, 277, São Paulo, SP, 05508-090, Brazil.
Background: In this study, we investigated the genetic variability and population structure of the New World screwworm fly Cochliomyia hominivorax. We tested the hypothesis that the species exhibits a center-periphery distribution of genetic variability, with higher genetic diversity in central populations (e.g.
View Article and Find Full Text PDFMol Genet Genomics
January 2025
Institute of Agriculture, Academic Assembly Faculty, Shinshu University, 8304 Minamiminowa, Nagano, 399-4598, Japan.
Chili pepper (Capsicum spp.) fruits are used as vegetables, spices, and ornamental plants, necessitating various fruit characteristics. However, their genetic improvement is challenging through conventional crossbreeding due to the quantitative traits, which makes it difficult to predict phenotypes in the progeny.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!