A real-time thermoregulatory model using noninvasive measurements as inputs was developed for predicting physiological responses of individuals working long hours. The purpose of the model is to reduce heat-related injuries and illness by predicting the physiological effects of thermal stress on individuals while working. The model was originally validated mainly by using data from controlled laboratory studies. This study expands the validation of the model with field data from 26 test volunteers, including US Marines, Australian soldiers, and US wildland fire fighters (WLFF). These data encompass a range of environmental conditions (air temperature: 19-30° C; relative humidity: 25-63%) and clothing (i.e., battle dress uniform, chemical-biological protective garment, WLFF protective gear), while performing diverse activities (e.g., marksmanship, marching, extinguishing fires, and digging). The predicted core temperatures (Tc), calculated using environmental, anthropometric, clothing, and heart rate measures collected in the field as model inputs, were compared with subjects' Tc collected with ingested telemetry temperature pills. Root mean standard deviation (RMSD) values, used for goodness of fit comparisons, indicated that overall, the model predictions were in close agreement with the measured values (grand mean of RMSD: 0.15-0.38° C). Although the field data showed more individual variability in the physiological data relative to more controlled laboratory studies, this study showed that the performance of the model was adequate.
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http://dx.doi.org/10.1519/JSC.0b013e31825ceba4 | DOI Listing |
Adv Exp Med Biol
September 2024
Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
A new behavioral test was developed to investigate the neural mechanisms of voluntary, behavioral thermoregulatory responses. The apparatus used in this test consisted of a thermostatic chamber that maintained the ambient temperature at a chosen level and two side-by-side floor plates that were placed in the thermostatic chamber and could be set to different temperatures. As the three temperatures, ambient temperature and two plate temperatures, can be controlled independently, we term this behavioral test the three-temperature (3 T) test.
View Article and Find Full Text PDFJ Ethnopharmacol
April 2024
School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, China. Electronic address:
Ethnopharmacological Relevance: Tetrastigma hemsleyanum Diels et Gilg, is one of the perennial evergreen plants with grass vine, which has obvious curative effect on severe infectious diseases. Although Tetrastigma hemleyanum has long been recognized for its capacity of antipyretic and antitoxic, its specific mechanism is unknown.
Aim Of The Study: To evaluate the antipyretic effect of Tetrastigma hemleyanum polysaccharide (THP) on mice with dry yeast-induced fever, and to explore its specific antipyretic mechanism.
Measurements of the thermal properties of the skin can serve as the basis for a noninvasive, quantitative characterization of dermatological health and physiological status. Applications range from the detection of subtle spatiotemporal changes in skin temperature associated with thermoregulatory processes, to the evaluation of depth-dependent compositional properties and hydration levels, to the assessment of various features of microvascular/macrovascular blood flow. Examples of recent advances for performing such measurements include thin, skin-interfaced systems that enable continuous, real-time monitoring of the intrinsic thermal properties of the skin beyond its superficial layers, with a path to reliable, inexpensive instruments that offer potential for widespread use as diagnostic tools in clinical settings or in the home.
View Article and Find Full Text PDFComput Methods Programs Biomed
December 2022
School of Mechanical & Automotive Engineering, South China University of Technology, Guangzhou, Guangdong 510641, China; Guangdong Key Laboratory of Automotive Engineering, South China University of Technology, Guangzhou, Guangdong 510641, China. Electronic address:
Background And Objectives: Thermal conditions are changeable in cabin space, where occupants could suffer consecutive self-thermoregulation to such changing thermal stresses. Thermal environment management is expected to be purposefully auto-adjustable for the environment by recognizing individual real-time thermal sensations. Current thermal sensation evaluation models are developed for virtual simulations rather than for realistic scenarios, challenging to evaluate human thermal sensation in the field surveys.
View Article and Find Full Text PDFFront Pediatr
October 2022
Institute for Women's Health, University College London, London, United Kingdom.
Brain tissue temperature is a dynamic balance between heat generation from metabolism, passive loss of energy to the environment, and thermoregulatory processes such as perfusion. Perinatal brain injuries, particularly neonatal encephalopathy, and seizures, have a significant impact on the metabolic and haemodynamic state of the developing brain, and thereby likely induce changes in brain temperature. In healthy newborn brains, brain temperature is higher than the core temperature.
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