Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3122
Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Objective: To determine the prevalence and risk factors of functional constipation (FC) by using Rome III criteria in the local adult communities.
Methods: A stratified randomized and community-based study by multi-stage cluster sampling was employed. A household survey was conducted from April to May 2010. All of the participants were interviewed face-to-face by filling out the self-administered questionnaires which based on Rome III criteria for the diagnosis of FC. Self-rating anxiety scale (SAS), self-rating depression scale (SDS) and Athens insomnia scale (AIS) were carried out to evaluate the psychological characteristics and qualities of sleep.
Results: A total of 7648 subjects fulfilled the questionnaires, with the response rate as 90.0%. 211 patients met the Rome III criteria, including 90 males and 121 females. The adjusted prevalence rates of FC were 2.5% in males, 3.3% in females and with an overall rate as 2.9%. The ratio of men to women was 1:1.32, with significant difference between males and females (P=0.043). The most common group was in the 18-29 year-olds (χ2=37.359, P=0.000). FC patients were more likely to be detected in the group with normal BMI (χ2=16.087, P=0.002), having received high education (χ2=27.604, P=0.000), being intelectuals (χ2=6.922, P=0.031) and divorced (χ2=22.000, P=0.000) than in other groups. Multivariate analysis showed that excessive intake of high-fat food was significantly associated with the presence of FC (odds ratio as 1.253, P=0.000), whereas foods with high-fiber (odds ratio as 0.854, P=0.029) might serve as protective factors. Significant differences between FC groups and control groups were found in the incidence of anxiety (with odds ratio as 2.583, P=0.000) and insomnia (odds ratio as 2.443, P=0.000).
Conclusion: The prevalence of FC in adult communities in Shanghai Songjiang district was not higher than that in other parts of the communities. Excessive intake of high-fat food, anxiety and insomnia might be risk factors for FC and foods with high-fiber contents might serve as protective factors.
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