Malignant mesothelioma of the tunica vaginalis testis is a rare, but often fatal, malignancy that usually appears during the fourth decade and has a strong relationship with occupational exposure to asbestos and long-lasting hydrocele. We present a case involving a 36-year-old man without a history of hydrocele, trauma, or exposure to asbestos who developed malignant mesothelioma.
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Mesothelioma of the Tunica Vaginalis Testis: Diagnostic and Therapeutic Management. A Comprehensive Review, 1982-2024.
Cancers (Basel)
November 2024
Occupational Health Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Background: Mesothelioma of the tunica vaginalis testis (MTVT) is an extremely rare and aggressive cancer. The diagnosis and management of MTVT is complex, and no standard treatment protocol is available.
Methods: We conducted a systematic literature review from 1 January 1982 to 14 March 2024 using PubMed to collect all the available case reports and case series.
Metastatic Mesothelioma of the Tunica Vaginalis Presenting as Scrotal and Abdominal Nodules: A Case Report and Review of the Literature.
Am J Dermatopathol
January 2025
Department of Pathology, Stanford University School of Medicine, Stanford, CA.
Article Synopsis
- Mesothelioma of the tunica vaginalis testis (MMTVT) is a rare type of malignant mesothelioma, making up less than 3% of cases, and is linked to asbestos exposure, similar to pleural mesothelioma, but tends to have a better prognosis.
- The case presented involves a 67-year-old man with a history of asbestos exposure, who exhibited scrotal pain and unusual skin growths; diagnostic methods confirmed the presence of mesothelioma through specific immunohistochemical markers.
- Genetic testing revealed common alterations associated with malignant mesothelioma, and imaging suggested primary MMTVT, indicating this case involved cutaneous metastases to
Malignant Mesothelioma of the Tunica Vaginalis: About a Rare Clinical Case.
Cureus
September 2024
Urology, Centro Hospitalar Universitário de Lisboa Central, Lisbon, PRT.
Malignant mesothelioma (MM) of the tunica vaginalis is an exceedingly rare neoplasm, with fewer than 300 cases reported in the medical literature. Due to its rarity, epidemiology, and risk factors are still unclear, and it is unknown whether asbestos or chronic inflammatory conditions play a role in etiology. This case study presents a 70-year-old male patient with MM of the tunica vaginalis, detailing the diagnostic challenges, treatment procedures, and eventual progression to palliative care.
View Article and Find Full Text PDF[Well-differentiated papillary mesothelial tumour of the tunica vaginalis: A case report].
Beijing Da Xue Xue Bao Yi Xue Ban
August 2024
Department of Urology, Peking University Third Hospital, Beijing 100191, China.
Article Synopsis
- The mesothelium is a layer of cells covering serosal cavities, and mesothelial tumors are rare, especially those in the tunica vaginalis compared to other areas like the pleura or peritoneum.
- Mesothelial tumors in the tunica vaginalis are classified into three categories: adenomatoid tumors, well-differentiated papillary mesothelial tumors (WDPMT), and mesotheliomas, with WDPMT being particularly rare and lacking established treatment guidelines.
- A case of a 29-year-old man with chronic scrotal pain led to an emergency operation, revealing signs consistent with WDPMT, which was confirmed through postoperative histopathology and immunohistochemical staining.
Local Cutaneous Scrotal Involvement of Paratesticular Mesothelioma.
Am J Dermatopathol
October 2024
Departments of Dermatology, and.
Paratesticular mesothelioma (malignant mesothelioma arising from the tunica vaginalis of the testis) represents a small proportion of mesothelial neoplasms, and cutaneous involvement by paratesticular mesothelioma is very rare. Cutaneous involvement can manifest as scrotal subcutaneous nodules from regional spread, distant metastasis, or direct extension through surgical scars. Mesothelioma has 3 histopathologic classifications that include epithelioid, biphasic, and sarcomatoid, which is rarely seen in paratesticular mesothelioma.
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