Old antibiotics target TB with a new trick.

Cell Host Microbe

Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.

Published: May 2012

Autophagy is now recognized as a cellular defense mechanism that can restrict the growth of Mycobacterium tuberculosis (Mtb). In this issue of Cell Host & Microbe, Kim et al. (2012) demonstrate that antibiotics routinely used to treat Mtb infection elicit a host autophagy response critical for bacterial clearance.

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http://dx.doi.org/10.1016/j.chom.2012.05.002DOI Listing

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