The authors report a fatal case of Corynebacterium sp. endocarditis. Corynebacterium spp. are non-sporulating, pleomorphic Gram-positive bacilli. In particular the authors have identified a species of Corynebacterium very closely related to C striatum. This is C simulans. The authors were able to identify the genus and species using various phenotypic tests. Highlighted here is the importance of identifying diphtheroids as a significant pathogen in the appropriate setting and the need to start antibiotic therapy if this is suspected.
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http://dx.doi.org/10.1136/bcr.10.2011.4894 | DOI Listing |
Corynebacterium or diphtheroid's are gram-positive aerobic, pleomorphic skin and mucosal membrane components that are not pathogenic in nature. Peptostreptococcus indolicus belongs to the Peptostreptococcus genus and is a Gram-Positive Anaerobic Cocci (GPAC). Less than one percent of endocarditis is caused by gram-positive anaerobic bacteria.
View Article and Find Full Text PDFFront Cardiovasc Med
November 2021
Department of Cardiac Surgery, First Affiliated Hospital, China Medical University, Shenyang, China.
We herein present a case of infective endocarditis of the mitral valve and a paravalvular abscess around the tricuspid valve. Preoperative blood culture confirmed the presence of pathogenic diphtheroids. During the operation, an unexpected infection of the free wall of the right atrium (RA) near the tricuspid annulus was found.
View Article and Find Full Text PDFJ Microsc Ultrastruct
November 2020
Department of Internal Medicine, Saint Vincent Hospital, Worcester, Massachusetts, USA.
Introduction: is a Gram-positive, catalase- and oxidase-negative, microaerophilic, nonmotile bacteria species rarely associated with human infections such as arthritis, bacteremia, endocarditis, and meningitis. The bacteria are also often confused with streptococci species or treated as a contaminant.
Patients And Methodology: We conducted a retrospective, observational cohort study on all patients with isolates in blood samples from July 2010 to June 2019.
IDCases
November 2017
Cardiology Department, MedStar Washington Hospital Center, United States.
Diphtheroids are gram-positive pleomorphic bacilli in the family of Coryneform bacteria. These organisms are present as part of the human flora. Past practice habits had been to consider them as contaminants when isolated from clinical samples.
View Article and Find Full Text PDFCureus
November 2015
Department of Microbiology, Prathima Institute of Medical Sciences.
Isolation of diphtheroids in human clinical specimens is not uncommon. Several studies have highlighted the significance of these bacteria in human infection, which morphologically resemble Corynebacterium diphtheriae. Previous studies have noted that occurrence of these bacteria in specimens like the blood should not be ignored as they can result in serious infections like endocarditis and sepsis among debilitated individuals, including the neonates.
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