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The Severity of Prostaglandin-Associated Periorbitopathy Did Not Affect the Surgical Effectiveness of the Ahmed Glaucoma Valve.
J Clin Med
December 2024
Department of Ophthalmology, Shimane University Faculty of Medicine, Izumo 693-8501, Japan.
: To report the role of prostaglandin-associated periorbitopathy (PAP) severity on the surgical efficacy of Ahmed Glaucoma Valve (AGV) implantation. : Retrospective observational case series. Participants were the consecutive 102 eyes from 102 Japanese subjects (55 males, 47 females; mean age ± standard deviation, 74.
View Article and Find Full Text PDFHepatic arterial infusion chemotherapy enhances the efficacy of lenvatinib and PD-1 inhibitors for advanced hepatocellular carcinoma: A meta-analysis and trial sequential analysis.
Eur J Surg Oncol
January 2025
Department of Hepato-biliary-pancrease II, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, 637000, PR China. Electronic address:
Background: Hepatic arterial infusion chemotherapy (HAIC) was an effective treatment for advanced hepatocellular carcinoma (HCC), and its effectiveness in combination with targeted immunotherapy regimens was controversial. This meta-analysis was performed to evaluate the efficacy of adding HAIC to lenvatinib in combination with programmed death-1 (PD-1) inhibitors.
Methods: Literature related to the efficacy of HAIC in combination with lenvatinib plus PD-1 inhibitors in the treatment of advanced HCC was searched through PubMed, Cochrane Library, Embase, and Web of Science databases.
Adjusted curves for clustered survival and competing risks data.
Commun Stat Simul Comput
August 2023
Division of Biostatistics, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Observational studies with right-censored data often have clustered data due to matched pairs or a study center effect. In such data, there may be an imbalance in patient characteristics between treatment groups, where Kaplan-Meier curves or unadjusted cumulative incidence curves can be misleading and may not represent the average patient on a given treatment arm. Adjusted curves are desirable to appropriately display survival or cumulative incidence curves in this case.
View Article and Find Full Text PDFPromoting Wellness Among Orthopaedic Surgeons.
JB JS Open Access
January 2025
Department of Orthopaedic Surgery and Rehabilitation, Loyola University Medical Center, Maywood, Illinois.
» Wellness encompasses multiple dimensions of well-being, including physical, mental, emotional, social, and spiritual health. Prioritizing physician wellness is crucial for ensuring high-quality patient care and reducing the risks of burnout, depression, and other mental health issues. Poor wellness among physicians not only affects their personal and professional lives but also has a ripple effect on patient care.
View Article and Find Full Text PDFExploring Occupational Health Challenges in Pathology: A Cross-Sectional Survey of Indian Pathologists.
Cureus
December 2024
Pathology, BLDE (Deemed to be University) Shri B.M. Patil Medical College, Hospital, and Research Centre, Vijayapura, IND.
Introduction Occupational health hazards are a significant concern for pathologists due to their unique work environment. These professionals face risks from prolonged microscope use, exposure to chemicals such as formalin, and handling sharp instruments, leading to issues such as musculoskeletal disorders and needlestick injuries. Addressing these hazards is crucial for their well-being and the overall efficiency of medical diagnostics.
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