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http://dx.doi.org/10.1111/j.1442-2050.2012.01362.x | DOI Listing |
Cells Dev
December 2024
Center for Interdisciplinary Research in Biology (CIRB), Collège de France, CNRS, INSERM, Université PSL, Paris, France; School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
2024 not only marked the 100th anniversary of the discovery of the organizer by Hilde Pröscholdt-Mangold and Hans Spemann, but also the 40th anniversary of the discovery of the homeobox, a DNA region encoding a DNA binding peptide present in several transcription factors of critical importance for the gastrulating embryo. In particular, this sequence is found in the 39 members of the amniote Hox gene family, a series of genes activated in mid-gastrulation and involved in organizing morphologies along the extending anterior to posterior (AP) body axis. Over the past 30 years, the study of their coordinated regulation in various contexts has progressively revealed their surprising regulatory strategies, based on mechanisms acting in-cis, which can translate a linear distribution of series of genes along the chromatin fiber into the proper sequences of morphologies observed along our various body axes.
View Article and Find Full Text PDFCurr Issues Mol Biol
December 2024
Department of Pathology and Biomedical Science, University of Otago, Christchurch 8140, New Zealand.
(https://www [...
View Article and Find Full Text PDFTheriogenology
December 2024
Department of Clinical Studies - New Bolton Center, University of Pennsylvania School of Veterinary Medicine, Kennett Square, PA, 19348, USA.
In 2024, Theriogenology turned 50! The purpose of this special issue is to emphasize the pivotal role of reproduction and fertility in improving the efficacy and sustainability of animal production in a range of environments (different production systems, different climates, or different consumer-related expectations). A first series of articles summarizes the possibilities and constraints linked to embryo production (in vivo and in vitro) as well as the potential of novel embryo technologies. A second series provides an overview of the future of production and reproduction for the next 20 years in different species and geographical areas.
View Article and Find Full Text PDFThe 50th anniversary of the is a milestone that calls for reflection on the many important contributions made by our clinicians, educators, and researchers to the care of older adults. This article was written to highlight not only the issues that have been the focus of our professional attention but also the accomplishments that gerontological nurses have made during the past half century. Edna Stilwell, the inaugural editor, laid out nine objectives for the journal in the first issue, which was published in 1975.
View Article and Find Full Text PDFThe World Health Organization recognizes that aging is a life-long process. Aging is a universal phenomenon, and the number of people aged ≥65 years is expected to increase exponentially over the next 30 to 50 years. Thus, the universality and globalization of aging requires that our interconnected societies be equipped to meet the needs of humans across all developmental and life stages.
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