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A Rare Cutaneous Manifestation of Systemic Sclerosis.
Eur J Case Rep Intern Med
October 2024
Department of Dermatology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New York, USA.
Unlabelled: A 43-year-old male with a history of intravenous drug use and alcohol consumption presented to the emergency department with three-month history of failure to thrive. The patient exhibited a constellation of constitutional symptoms including cough, weight loss, fatigue, decreased appetite, nausea and vomiting. The skin examination revealed multiple subcutaneous hyperpigmented, indurated plaques and nodules on the trunk and arms.
View Article and Find Full Text PDFNodular scleroderma: Characterization of a distinct clinical phenotype.
Am J Med Sci
September 2024
Division of Rheumatology, Department of Medicine, Thomas Jefferson University, 211 S 9th St Suite 210, Philadelphia, PA 19107, United States; Jefferson Institute of Molecular Medicine and Scleroderma Center, Thomas Jefferson University, Philadelphia, PA, United States. Electronic address:
Article Synopsis
- Nodular scleroderma is a rare form of systemic sclerosis marked by hard, fleshy nodules mainly on arms, legs, and trunk, and is often confused with keloid variants, though distinctions have been made recently.
- It typically appears alongside other systemic sclerosis symptoms, especially in individuals with the diffuse systemic sclerosis phenotype, and presents early during skin changes.
- Patients usually have specific antinuclear antibodies but show a low incidence of pulmonary hypertension, with standard treatments not effectively reducing the nodules.
Use of artificial intelligence algorithms to analyse systemic sclerosis-interstitial lung disease imaging features.
Rheumatol Int
October 2024
Department of Rheumatology, People's Hospital of Xiangxi Tujia and Miao Autonomous Prefecture (The First Affiliated Hospital of Jishou University), Intersection of Shiji Avenue and Jianxin Road, Jishou, 416000, Hunan, People's Republic of China.
The use of artificial intelligence (AI) in high-resolution computed tomography (HRCT) for diagnosing systemic sclerosis-associated interstitial lung disease (SSc-ILD) is relatively limited. This study aimed to analyse lung HRCT images of patients with systemic sclerosis with interstitial lung disease (SSc-ILD) using artificial intelligence (AI), conduct correlation analysis with clinical manifestations and prognosis, and explore the features and prognosis of SSc-ILD. Overall, 72 lung HRCT images and clinical data of 58 patients with SSC-ILD were collected.
View Article and Find Full Text PDFNodular scleroderma partially controlled with tofacitinib.
An Bras Dermatol
August 2024
Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Electronic address:
Nodular (keloidal) scleroderma: A case series of 5 patients.
JAAD Case Rep
July 2024
Department of Dermatology, Weill Cornell Medical Center, New York, New York.
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