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What are parents' preferences for Human Papillomavirus vaccination promotion messages and communication? Application of a discrete choice experiment to a French Caribbean setting.
BMC Public Health
January 2025
Emerging Disease Epidemiology Unit, Institut Pasteur, Université Paris Cité, Paris, 7572, France.
Introduction: Human Papillomavirus (HPV) vaccine uptake in the French Caribbean has remained below 25% since introduction in 2007, which is well behind national and international targets. Using a discrete choice experiment (DCE), we explored parental preferences around HPV vaccination and optimized communication content in a sample of parents of middle-school pupils in Guadeloupe.
Methods: We conducted a cross-sectional survey in public and private middle age schools in Guadeloupe in June 2023 using an online questionnaire.
AI-driven automated discovery tools reveal diverse behavioral competencies of biological networks.
Elife
January 2025
Allen Discovery Center, Tufts University, Medford, United States.
Many applications in biomedicine and synthetic bioengineering rely on understanding, mapping, predicting, and controlling the complex behavior of chemical and genetic networks. The emerging field of diverse intelligence investigates the problem-solving capacities of unconventional agents. However, few quantitative tools exist for exploring the competencies of non-conventional systems.
View Article and Find Full Text PDFIdentifying biomarker-driven subphenotypes of cardiogenic shock: analysis of prospective cohorts and randomized controlled trials.
EClinicalMedicine
January 2025
University of Paris Cité, Inserm UMR-S 942, Cardiovascular Markers in Stress Conditions (MASCOT), Paris, France.
Background: Cardiogenic shock (CS) is a heterogeneous clinical syndrome, making it challenging to predict patient trajectory and response to treatment. This study aims to identify biological/molecular CS subphenotypes, evaluate their association with outcome, and explore their impact on heterogeneity of treatment effect (ShockCO-OP, NCT06376318).
Methods: We used unsupervised clustering to integrate plasma biomarker data from two prospective cohorts of CS patients: CardShock (N = 205 [2010-2012, NCT01374867]) and the French and European Outcome reGistry in Intensive Care Units (FROG-ICU) (N = 228 [2011-2013, NCT01367093]) to determine the optimal number of classes.
DNA methylation landscapes before and after Pacific Oyster Mortality Syndrome are different within and between resistant and susceptible Magallana gigas.
Sci Total Environ
January 2025
IHPE, Univ Montpellier, CNRS, IFREMER, Univ Perpignan Via Domitia, Montpellier, France. Electronic address:
Pacific oysters face recurring outbreaks of Pacific Oyster Mortality Syndrome (POMS), a polymicrobial multifactorial disease. Although this interaction is increasingly understood, the role of epigenetics (e.g.
View Article and Find Full Text PDFInvestigation of the Relationship Between Intolerance of Uncertainty, Metacognitions, Maladaptive Coping, and Fear of Cancer Recurrence via Moderated Mediation Model.
Psychooncology
January 2025
Department of Psychology, Maltepe University, İstanbul, Turkey.
Objective: In recent years, many studies have investigated the triggers, perpetuating factors, and outcomes of Fear of Cancer Recurrence (FCR), highlighting its complexity with multiple dimensions that encompass both antecedents and consequences. In this sense, the cognitive approach to FCR has explored variables such as metacognition, maladaptive coping strategies, and intolerance of uncertainty (IU). On the other hand, the findings of a restricted number of studies investigating the relationship between FCR and stated variables appear to be inconsistent.
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