Individuals with MCI declined in performance over 6 months in the Clock-drawing (Clox 1) and the WAIS Digit Span tests, but not in the Dementia Rating Scale (DRS). Individual performance on Clox 1 and Digit Span did not correlate after 6 months. Performance on the Digit Span Test also did not correlate with the DRS, but performance on Clox 1 correlated with the DRS. Performance in Clox 1 was, therefore, not a predictor of performance in the Digit Span Test. These findings support the use of a test battery containing the Digit Span test to detect and track cognitive decline in MCI.
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http://dx.doi.org/10.1155/2012/829743 | DOI Listing |
Alzheimers Dement
December 2024
Texas A&M University, College Station, TX, USA.
Background: Older females, particularly susceptible to Alzheimer's disease (AD), may be affected by hormonal fluctuation during life. We aim to investigate the relationship between changes in brain volume and sex steroid hormones over time. We hypothesize that levels of sex hormones (17ß-estradiol, progesterone, and testosterone) relate to changes in brain volume, especially in the hippocampus (HPC) and cerebellum (CB).
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Michigan, Ann Arbor, MI, USA.
Background: Menopause is a time of accelerated loss of physical function, illustrated by challenges to mobility, speed, strength, and performance of activities of daily living. Physical function is associated with cognitive function, but there are limited data exploring this association among older women. In a cohort of older adult women, we hypothesize better performance on measures of physical function will be associated with better cognitive performance.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of North Texas Health Science Center, Fort Worth, TX, USA.
Background: The concept of motoric cognitive risk (MCR) combines subjective cognitive concern (SCC) with slowed gait speed. The concept allows for the incorporation of cognitive and functional slowing into a measure of risk assessment. This study explores differences in cognitive functioning in cognitively unimpaired older adults with MCR and those without subjective cognitive concern and without slow gait speed.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, School of Life Science and Technology, University of Electronic Science and Technology of China, ChengDu, China.
Background: To examine whether walking speed is associated with executive function in patients with subjective memory decline.
Method: Patients were recruited from the Fourth People's Hospital of Chengdu, including 63 patients with subjective cognitive decline (SCD) and 23 patients with mild cognitive impairment (MCI). Each participant assess global function by the Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment-Basic Scale (MoCA-B).
Alzheimers Dement
December 2024
University of North Texas Health Science Center, Fort Worth, TX, USA.
Background: Mild cognitive function (MCI) is associated with a declined short-term memory (STM). This study compared STM between adults with MCI and normal cognition assessed by verbal memory vs visuospatial memory.
Methods: Sixteen subjects with MCI and 11 subjects with normal cognition gave their written consent to participate in the study which was approved by the North Texas Regional IRB.
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