This paper proposes a method to quantitatively measure and evaluate finger tapping movements for the assessment of motor function using log-linearized Gaussian mixture networks (LLGMNs). First, finger tapping movements are measured using magnetic sensors, and eleven indices are computed for evaluation. After standardizing these indices based on those of normal subjects, they are input to LLGMNs to assess motor function. Then, motor ability is probabilistically discriminated to determine whether it is normal or not using a classifier combined with the output of multiple LLGMNs based on bagging and entropy. This paper reports on evaluation and discrimination experiments performed on finger tapping movements in 33 Parkinson's disease (PD) patients and 32 normal elderly subjects. The results showed that the patients could be classified correctly in terms of their impairment status with a high degree of accuracy (average rate: 93.1 ± 3.69%) using 12 LLGMNs, which was about 5% higher than the results obtained using a single LLGMN.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345846 | PMC |
http://dx.doi.org/10.3390/s90302187 | DOI Listing |
Sci Rep
January 2025
Department of Life Sciences, The University of Tokyo, Tokyo, Japan.
Many theories of time perception propose the existence of an internal pacemaker, and studies across behavioral, physiological, and neuroscience fields have explored this concept. Specifically, Spontaneous Motor Tempo (SMT), the most comfortable and natural tapping tempo for each individual, is thought to reflect this internal pacemaker's tempo. Changes in heart rate are also linked to time estimation, while Individual Alpha Frequency (IAF), the peak in the alpha range (8-13 Hz) observed in EEG, is reported to reflect the brain's temporal processing.
View Article and Find Full Text PDFSleep Adv
December 2024
Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Study Objectives: Sleep spindles, defining electroencephalographic oscillations of nonrapid eye movement (NREM) stage 2 sleep (N2), mediate sleep-dependent memory consolidation (SDMC). Spindles are also thought to protect sleep continuity by suppressing thalamocortical sensory relay. Schizophrenia is characterized by spindle deficits and a correlated reduction of SDMC.
View Article and Find Full Text PDFACS Nano
January 2025
School of Engineering, RMIT University, 124 La Trobe Street, Melbourne, Victoria 3001, Australia.
Modern-day applications demand onboard electricity generation that can be achieved using piezoelectric phenomena. Reducing the dimensionality of materials is a pathway to enhancing the piezoelectric properties. Transition-metal dichalcogenides have been shown to exhibit high piezoelectricity.
View Article and Find Full Text PDFSensors (Basel)
December 2024
Department of Engineering, University of Napoli Parthenope, Centro Direzionale, 80143 Napoli, Italy.
In the context of neurodegenerative diseases, finger tapping is a gold-standard test used by clinicians to evaluate the severity of the condition. The finger tapping test involves repetitive tapping between the index finger and thumb. Subjects affected by neurodegenerative diseases, such as Parkinson's disease, often exhibit symptoms like bradykinesia, rigidity, and tremor.
View Article and Find Full Text PDFJ Neurosci
January 2025
Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, 40225 Germany
Recordings from Parkinson's disease (PD) patients typically show strong beta-band oscillations (13-35Hz), which can be modulated by deep brain stimulation (DBS). While high-frequency DBS (>100Hz) ameliorates motor symptoms and reduces beta activity in basal ganglia and motor cortex, the effects of low-frequency DBS (<30Hz) are less clear. Clarifying these effects is relevant for the debate about the role of beta oscillations in motor slowing, which might be causal or epiphenomenal.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!