We report a series of 14 cases of nail unit squamous cell carcinoma in situ/ Bowen's disease and squamous cell carcinoma (SCC) treated with Mohs micrographic surgery (MMS). MMS has been previously reported as an ideal treatment for nail unit SCC. This series adds to the current literature substantiating this claim, and also demonstrates the good outcomes achieved with secondary intention healing.
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http://dx.doi.org/10.1111/j.1440-0960.2011.00813.x | DOI Listing |
Front Immunol
January 2025
Rheumatology Unit, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
This pilot study investigates distinctive features within the nail-enthesis complex among Psoriatic arthritis (PsA), Psoriasis (PSO), Rheumatoid Arthrit is (RA), and Healthy Control (HC) groups, utilizing a combined approach of ultrasound (US) and nailfold videocapillaroscopy (NVC). Clinical assessments and comprehensive US and NVC evaluations of the nail-enthesis complex were conducted on 72 subjects (18 PsA, 16 PSO, 19 RA, 19 HC). Unsupervised clustering models and factor analysis were employed to identify patterns and interrelationships between US and NVC parameters.
View Article and Find Full Text PDFJ Fungi (Basel)
January 2025
DYNAMYC UR 7380, Faculté de Santé, Université Paris-Est Créteil (UPEC), 94010 Créteil, France.
We read the review by Gupta et al [...
View Article and Find Full Text PDFJ Am Acad Dermatol
January 2025
Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA. Electronic address:
Background: Nail unit melanoma (NUM) is increasingly treated with digit-sparing surgery, but few published case series describe Mohs micrographic surgery (MMS) for NUM.
Objective: To describe the surgical technique, local recurrence rates, and reconstruction method for a large series of NUM treated with MMS using MART-1 immunostaining.
Methods: Biopsy-proven NUM treated with MMS-MART-1 were identified from a prospectively maintained database (2008-2023).
Dermatol Ther (Heidelb)
January 2025
Department of Clinical and Molecular Sciences-Dermatological Clinic, Università Politecnica Delle Marche, Ancona, Italy.
Introduction: Palmoplantar psoriasis (PPp) has a profound negative impact on patients' quality of life, and it represents a therapeutic challenge, as palms and soles are difficult to treat area. Although the efficacy profile of tildrakizumab has been well evaluated in the literature, data on its use for PPp are still limited. The objective of the study was to evaluate the efficacy and safety of tildrakizumab on moderate-to-severe plaque psoriasis with involvement of the palmoplantar area.
View Article and Find Full Text PDFJ Am Acad Dermatol
January 2025
Department of Dermatology, Weill Cornell Medicine, New York, New York. Electronic address:
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