Smoking increases the risk of forming, growing, and rupture of intracranial aneurysms. We retrospectively reviewed patients with intracranial aneurysms treated by neurosurgical or endovascular treatment--154 patients (45 men, 109 women, 15 to 62 years, average 46.3 years, CI +/- 1.72). We found 74% (114/154) of smokers--80% (36/45) men and 71.6% (78/109) women, with the mean value of the Fagerström Test of Nicotine Dependence 4.4 (CI +/- 0.40). The average age of smoking initiation was 18.2 years (CI +/- 0.66), the average period of smoking 26.8 years (CI +/- 2.13). The average number of cigarettes consumed daily was 18.2 (CI +/- 1.58). With statistical significance p < 0.05, the athero-index was lower in nonsmokers than smokers: 3.4 (CI +/- 0.56) vs. 4.5 (CI +/- 0.51). HDL cholesterol was higher in non-smokers than smokers: 1.6 mmol/L (CI +/- 0.25) vs. 1.4 (CI +/- 0.10), and triglycerides were higher in smokers than non-smokers: 1.3 mmol/l (CI +/- 0.16) vs. 1.9 (CI +/- 0.35). Forty-two per cent of smokers (48/114) were controlled one year after the treatment; 18.8% of them stopped smoking, 41.7% reduced smoking, and 39.6% continued to smoke as extensively as before. The prevalence of smoking in our sample was higher than in the Czech population (28.2%). Only 18.8% of controlled smokers were able to quit one year after the intervention.

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http://dx.doi.org/10.21101/cejph.a3670DOI Listing

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