AI Article Synopsis
- The study investigates how various nuclear dyes (orsein, light green, methylene blue, and azure-eosin by Romanovsky-Giemsa) affect the detection of nuclear disorders in human buccal mucosa cells.
- Romanovsky-Giemsa dye was found to be the most effective, providing higher quality micropreparations and a wider range of identified abnormalities.
- The research highlights the importance of choosing the right dye for accurate assessment of nuclear disorders in cellular studies.
Article Abstract
The effect of staining with commonly used nuclear dyes (orsein, light green, methylene blue, azure-eosin by Romanovsky-Giemsa) on the frequency of occurrence of nuclear disorders (micronuclei, perinuclear vacuoles, notches, protrusions, such as "tongue" and "broken egg") in human buccal mucosa was determined. It is shown that Romanovsky-Giemsa dye is the best type of dye both in the quality of the micropreparations and the spectrum of detected abnormalities.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Optical molecular imaging in oral- and oropharyngeal squamous cell carcinoma using a novel uPAR-targeting near-infrared imaging agent FG001 (ICG-Glu-Glu-AE105): An explorative phase II clinical trial.
Theranostics
January 2025
Department of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging (CMI), Copenhagen University Hospital, Rigshospitalet & Department of Biomedical Sciences, University of Copenhagen, Denmark.
: In oral and oropharyngeal squamous cell carcinoma (OSCC, OPSCC), frequent inadequate surgical margins highlight the importance of precise intraoperative identification and delineation of cancerous tissue for improving patient outcomes. : A prospective, open-label, single-center, single dose, exploratory phase II clinical trial (EudraCT 2022-001361-12) to assess the efficacy of the novel uPAR-targeting near-infrared imaging agent, FG001, for intraoperative detection of OSCC and OPSCC. Macroscopic tumor detection was quantified with sensitivity and intraoperative tumor-to-background ratio (TBR).
View Article and Find Full Text PDFNetwork Pharmacology and Metabolomics Reveal Anti-Ferroptotic Effects of Curcumin in Acute Kidney Injury.
Drug Des Devel Ther
December 2024
Research Center of Innovation, Entrepreneurship, Minjiang University, Fuzhou, 350100, People's Republic of China.
Introduction: Acute kidney injury (AKI) is linked to high rates of mortality and morbidity worldwide thereby posing a major public health problem. Evidences suggest that ferroptosis is the primary cause of AKI, while inhibition of monoamine oxidase A(MAOA) and 5-hydroxytryptamine were recognized as the defender of ferroptosis. Curcumin (Cur) is a natural polyphenol and the main bioactive compound of , which has been found nephroprotection in AKI.
View Article and Find Full Text PDFSolar driven enhanced adsorption of radioactive Cs and Sr from nuclear wastewater by chitosan-based aerogel embedded with prussian blue analog.
J Hazard Mater
December 2024
College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin 150001, China; Nanhai Institute of Harbin Engineering University, Sanya 572024, China. Electronic address:
The rational use of solar energy to achieve photothermal conversion is an attractive strategy to promote the efficient removal of radioactive Cs and Sr from nuclear wastewater. Herein, a photothermal adsorbent of composite aerogel with three-dimensional porous structure is fabricated by integrating prussian blue analogues (PBAs) and straw biochar into the chitosan (CS) and waste leather scrap hydrolysate (WLSH) aerogel matrix (CS/WLSH/C/PBAs). The local heating effect generated by CS/WLSH/C/PBAs aerogel induce to generate steam, accelerating the enrichment of Cs and Sr in the solution, which increase their interaction with the CS/WLSH/C/PBAs and improves their adsorption rates and capacities.
View Article and Find Full Text PDFFacile Synthesis of Silsesquioxane-Based Hybrid Crosslinked Polymers via One-Step Amine-Ene Reaction for Efficient Adsorption of Various Pollutants.
Chem Asian J
December 2024
shandong university, chemistry, Shanda nanlu No.27, JInan, Shandong, jinan, CHINA.
The rapid advancement of industrial production has led to an increase in water pollutants, posing a significant threat to public health. With the deepening of research on pollutant adsorbents. The application of silsesquioxane-based cross-linked polymer networks in water pollution treatment has gradually attracted people's attention.
View Article and Find Full Text PDFVitamin C Ameliorates Potassium Dichromate-Induced Oxidative Stress and Mitochondrial Dysfunction via PGC-1α/Nrf-2/TFAM Pathway.
J Biochem Mol Toxicol
January 2025
Department of Anatomy, College of Medicine, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia.
Exposure to potassium dichromate (KCrO) is well known for its nephrotoxic effects on humans and animals. This study investigated the protective effects of vitamin C against KCrO-induced nephrotoxicity, focusing on its impact on altered carbohydrate metabolism, mitochondrial dysfunction, and associated molecular mechanisms in the cortical and medullary kidney segments. Male Wistar rats (n = 8) were divided into four groups: Group I received saline, Group II received a single 250 mg/kg body weight (bwt) intraperitoneal (i.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!