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Mood lability and depression limit oral contraceptive therapy in endometriosis.
Fertil Steril
December 2024
Obstetrics, Gynecology & Reproductive Sciences, Yale School of Medicine, New Haven, CT 06520.
Objective: To determine the impact of oral contraceptive (OC) induced mood lability/depression on treatment maintenance in women with endometriosis.
Design: Women with endometriosis were retrospectively identified through International Classification of Diseases-10 codes and then a comprehensive electronic medical record review was conducted, identifying mood lability/depression as a reason for treatment discontinuation with the use of combined or progestin-only oral contraceptives.
Subjects: 2,682 women with endometriosis, between the ages of 18-45 treated in a university affiliated hospital between 2012-2024.
Perioperative Hypotension in Chronic Kidney Disease Patients with Dialysis Undergoing Noncardiac Surgery: A Retrospective Cohort Study.
Anesthesiology
January 2025
Center of Outcomes Research and Department of Anesthesiology, Critical Care, and Pain Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas.
Background: Patients with chronic kidney disease who require maintenance dialysis suffer excess morbidity and mortality for reasons that are not clearly elucidated. There are few targets for intervention to improve their outcomes. The authors hypothesized that perioperative hypotension is more common in patients receiving dialysis.
View Article and Find Full Text PDFDeclining Prevalence of Human Papillomavirus Co-Infections Among Young Japanese Women With Cervical Cancer and Its Precursors.
J Med Virol
December 2024
Department of Obstetrics and Gynecology, Showa University School of Medicine, Tokyo, Japan.
Co-infections with human papillomavirus (HPV) of multiple genotypes mainly occur due to increased sexual activity. To address the prevalence and trend of HPV co-infections in Japan, HPV-type-specific data from Japanese women (n = 8128) aged < 40 years and newly diagnosed with cervical abnormalities at 24 hospitals between 2012 and 2023 were analyzed. These included cervical intraepithelial neoplasia grade 1/2 (CIN1/2, n = 2745), CIN3/adenocarcinoma in situ (AIS) (n = 3953), and invasive cervical cancer (ICC, n = 1430).
View Article and Find Full Text PDFPopulation-Based Study of the Epidemiology of Stiff Person Syndrome in a Large Colorado-Based Health System.
Neurology
December 2024
From the Department of Neurology (P.D.C., S.S.), and Department of Biostatistics & Informatics (S.S.), University of Colorado Anschutz Medical Campus; University of Colorado School of Medicine Anschutz Medical Campus (R.D., P.W., E.E., B.V., E.M., K.V.N., A.M.C., A.L.P.); University of Colorado School of Medicine (R.F.), Aurora; School of Osteopathic Medicine (R.F.), Kanas City University, MO; University of Colorado School of Medicine Anschutz Medical Campus (R.V.C.); School of Medicine (R.V.C.), Aurora, CO; Renown Health (R.V.C.), Reno, NV; Rocky Mountain MS Center (K.V.N., A.L.P.), University of Colorado School of Medicine; and Skaggs School of Pharmacy and Pharmaceutical Sciences (K.V.N.), University of Colorado Anschutz Medical Campus, Aurora.
Article Synopsis
- Stiff person syndrome spectrum disorder (SPSD) is a rare autoimmune condition with estimated prevalence of 1-2 cases per million, marked by muscle stiffness and painful spasms; this study aims to clarify its incidence and prevalence using data from the University of Colorado Health system.
- A total of 273 patients were identified with potential SPSD diagnosis codes, but only 59 were confirmed to have the disorder, leading to a prevalence estimate of 2.11 cases per 100,000 persons.
- Different clinical diagnostic criteria were assessed, revealing varying estimated prevalence rates for SPSD, indicating inconsistencies in diagnosis and classification within the population studied.
Epidemiology of hospitalized heart failure in France based on national data over 10 years, 2012-2022.
ESC Heart Fail
November 2024
Santé Publique France, Saint-Maurice, France.
Article Synopsis
- The study investigates heart failure (HF) hospitalization in France post-pandemic, focusing on incidence, prevalence, patient characteristics, management, and outcomes based on sex, age, and socio-economic status.
- Utilizing a comprehensive health care database, findings reveal a prevalence rate of 1.7% in France, with an overall decrease in acute HF decompensation incidence since 2012, particularly among men under 45.
- Despite improvements in management and a decline in one-year rehospitalization rates, one-year mortality rates remain high, especially among younger women and the most deprived areas.
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