Primary Extra-gastrointestinal Stromal Tumor of Retroperitoneum.

Clin Med Insights Oncol

Department of Medical and Surgical Sciences, University of Brescia, 1st Division of General Surgery-Spedali Civili Brescia, Brescia, Italy.

Published: August 2012

Background: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract. More rarely neoplasms with histology and immunohistochemistry similar to GISTs may occur outside the gastrointestinal tract ( omentum, mesentery and retroperitoneum) and are so-called Extra-gastrointestinal Stromal Tumors (EGISTs). EGISTs arising in the retroperitoneum are extremely rare: to date, only 58 cases have been reported in the literature.

Case Report: We herein report a case of a primary EGIST of the retroperitoneum surgically treated. The pre-operative radiological evaluation showed a retroperitoneal mass, placed in left paravertebral region.

Results: Morphological and immunohistochemical features led to a diagnosis of extra-gastrointestinal stromal tumor (intermediate-low risk form).

Conclusions: As a result of the rarity of reports of primary EGISTs of retroperitoneum we need to analyze the data of reported cases in order to gain a better understanding about the pathogenesis, prognosis and optimal treatment of this disease.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342024PMC
http://dx.doi.org/10.4137/CMO.S9180DOI Listing

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