Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.leukres.2012.04.004 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Pathophysiology and classification of iron overload diseases; update 2018.
Transfus Clin Biol
February 2019
Service d'hématologie clinique et de thérapie cellulaire, faculté de médecine, hôpital Saint-Antoine, Sorbonne université, Inserm UMRs-938 centre de recherche Saint-Antoine, AP-HP, 75012 Paris, France. Electronic address:
Iron overload pathophysiology has benefited from significant advances in the knowledge of iron metabolism and in molecular genetics. As a consequence, iron overload nosology has been revisited. The hematologist may be confronted to a number of iron overload syndromes, from genetic or acquired origin.
View Article and Find Full Text PDF[Copper deficiency anemia morphologically mimicking myelodysplastic syndrome].
Rinsho Ketsueki
March 2014
Division of Hematology, Department of Medicine, Keio University School of Medicine.
A 64-year-old man underwent kidney transplantation for progressive chronic renal failure which had developed 8 years after allogeneic bone marrow transplantation for acute myeloid leukemia. Because of post-operative complications, he had been placed on intravenous hyperalimentation. Three months after the transplantation, anemia rapidly progressed (hemoglobin, 7.
View Article and Find Full Text PDFClinicopathological analysis of myelodysplastic syndrome according to French-American-British classification.
J Coll Physicians Surg Pak
May 2010
Department of Haematology, Sheikh Zayed Postgraduate Medical Institute, Lahore.
Objective: To evaluate the age of onset, gender ratio, clinical presentation of Myelodysplastic syndrome patients, and to classify these patients according to French-American-British classification on the basis of morphological features in blood and bone marrow.
Study Design: A case series.
Place And Duration Of Study: The Department of Haematology, Shaikh Zayed Hospital, Lahore, from April 2004 to March, 2007.
Human iron-sulfur cluster assembly, cellular iron homeostasis, and disease.
Biochemistry
June 2010
Molecular Medicine Program, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.
Iron-sulfur (Fe-S) proteins contain prosthetic groups consisting of two or more iron atoms bridged by sulfur ligands, which facilitate multiple functions, including redox activity, enzymatic function, and maintenance of structural integrity. More than 20 proteins are involved in the biosynthesis of iron-sulfur clusters in eukaryotes. Defective Fe-S cluster synthesis not only affects activities of many iron-sulfur enzymes, such as aconitase and succinate dehydrogenase, but also alters the regulation of cellular iron homeostasis, causing both mitochondrial iron overload and cytosolic iron deficiency.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!