Leaves of Atalantia monophylla are used in chronic rheumatism and paralysis. The Pharmacognostical studies like histological characters, leaf constants, ash values and extractive values of leaves of Atalantia monophylla Corr were carried out. The preliminary phytochemical analysis were also carried out.
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ACS Omega
December 2024
National Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, Mississippi 38677-1848, United States.
Despite promising preliminary biology, natural products isolation efforts may be confounded when the active compound is not isolated during bioassay-guided purification or classical pharmacognostic research investigations. A more rational isolation procedure connecting the polypharmacology of an herb to its individual constituents must be applied to better detect bioactive molecules before tedious analytical steps are considered. While (yohimbe) has been traditionally used in herbal medicine as a general tonic, an aphrodisiac, a performance enhancer, and an integral part of various dietary supplements, the hydroethanolic extract of yohimbe was identified to possess at least 3-4-fold induction of the pregnane X receptor (PXR) at 30 μg/mL, a key nuclear receptor implicated in adverse interactions, .
View Article and Find Full Text PDFMicrosc Res Tech
December 2024
Phytomedicine, Molecular Toxicology, and Computational Biochemistry Research Laboratory (PMTCB-RL), Department of Biochemistry, Bowen University, Iwo, Nigeria.
Croton lobatus L. and Croton zambesicus Mull. Arg.
View Article and Find Full Text PDFDose Response
December 2024
Department of Clinical Laboratory Science, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Background: is a multipurpose plant known for its remedial properties but the antimicrobial and hepatoprotective activity of its pods remained unexplored.
Objective: This study aimed to evaluate the antimicrobial and hepatoprotective activity of n-hexane (ANPH) and methanol (ANPM) extracts of pods to scientifically validate their medicinal claims.
Methods: After the pharmacognostic evaluation of pods, tests were carried out to estimate phenolic and flavonoid content and antimicrobial potential.
Microsc Res Tech
December 2024
Department of Pharmacy, COMSATS University Islamabad, Abbottabad, Khyber Pakhtunkhwa, Pakistan.
Traditional medicinal systems have extensively used Primula macrophylla (Primulaceae) to treat a variety conditions, including bronchitis, asthma, joint pain, fever and so forth. This study determines various pharmacognostic and phytochemical standards helpful to ensure the purity, safety, and efficacy of medicinal plant P. macrophylla.
View Article and Find Full Text PDFToxicol Rep
December 2024
Department of Pharmacology, Amity Institute of Pharmacy, Amity University Haryana, Gurugram, Haryana 122413, India.
Background: Psychiatric disorders like depression and anxiety are global challenges, exacerbated by the limitations of synthetic medications, including addiction and toxic side effects.
Methods: This study meticulously investigated the pharmacognostic, phytochemical, toxicological, and pharmacological properties of Callistemon viminalis Cheel. Toxicological assessments, including hemocompatibility assays, LD studies, FOB analysis, biochemical parameters, and structural integrity of vital organs, were conducted on aqueous, methanolic, chloroform, and petroleum ether extracts of leaves and stems.
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