Human infection due to Nocardiopsis, an actinomycete, is rare and the majority of those infections are due to Nocardiopsis dassonvillei. This agent has been implicated in cutaneous, pulmonary, eye and disseminated infections. It has never been isolated from the nose or any nasal infection. We report here a rare case of nasal vestibular abscess due to N. dassonvillei in an adult diabetic patient. The bacterium was identified on the basis of morphological and biochemical characteristics, and confirmed by sequencing the 16S rRNA and hsp65 genes. The patient was successfully treated with clarithromycin and levofloxacin. Though N. dassonvillei infections may be rare, the study highlights that it may cause a wide spectrum of disease manifestations, and laboratories should take care to isolate and identify the easily treatable pathogen.
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http://dx.doi.org/10.1099/jmm.0.038240-0 | DOI Listing |
J Basic Microbiol
December 2024
Pharmaceutical Biotechnology Division, A.U. College of Pharmaceutical Sciences, Andhra University, Visakhapatnam, Andhra Pradesh, India.
Petroleum and other oil manufacturing industries contribute to environmental pollution by releasing hazardous hydrocarbons. Biosurfactants offer a sustainable solution for mitigating oil pollution through emulsification processes, safeguarding agricultural soils, aquatic ecosystems, and human health. This study focuses on isolating, screening, and identifying actinomycetes producing biosurfactant from oil-polluted soil in the naval dockyard of Visakhapatnam.
View Article and Find Full Text PDF3 Biotech
October 2024
Department of Biotechnology with Jointly Merged Institute of Bioinformatics and Biotechnology, Savitribai Phule Pune University, Pune, 411007 India.
Unlabelled: In the current study, the ability of an indigenous marine Actinomycete (NCIM 5124) to degrade poly(3-hydroxybutyrate)-PHB was examined. From the whole genome sequencing data of the organism, information regarding the PHB depolymerase gene and amino acid sequence (Accession number: MCK9871921.1) was retrieved.
View Article and Find Full Text PDFAppl Biochem Biotechnol
August 2024
Department of Biosciences, Saurashtra University, Rajkot, 360005, Gujarat, India.
The oceanic actinobacteria have strong potential to secrete novel enzymes with unique properties useful for biotechnological applications. The Nocardiopsis dassonvillei strain VCS-4, associated with seaweed Caulerpa scalpeliformis, was a halo-alkaline protease producer. Further investigation focuses on medium optimization and the use of agro-industrial waste for economically feasible, high-yield protease production.
View Article and Find Full Text PDFGene
December 2024
Department of Biotechnology (with Jointly Merged Institute of Bioinformatics and Biotechnology), Savitribai Phule Pune University, Pune, India. Electronic address:
Since ectoine is a high-value product, overviewing strategies for identifying novel microbial sources becomes relevant. In the current study, by following a genome mining approach, the ectoine biosynthetic cluster in a tropical marine strain of Nocardiopsis dassonvillei (NCIM 5124) was located and compared with related organisms. Transcriptome analysis of Control and Test samples (with 0 and 5% NaCl, respectively) was carried out to understand salt induced stress response at the molecular level.
View Article and Find Full Text PDFRes Microbiol
May 2024
Department of Biotechnology (With Jointly Merged Institute of Bioinformatics and Biotechnology), Savitribai Phule Pune University, Pune, 411007, India. Electronic address:
Nocardiopsis dassonvillei prevails under harsh environmental conditions and the purpose of this review is to highlight its biological features and recent biotechnological applications. The organism prevails in salt-rich soils/marine systems and some strains endure extreme temperatures and pH. A few isolates are associated with marine organisms and others cause human diseases.
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