To look for a correlation between or the effect of anisometropia amblyopia on retrobulbar blood flow parameters. Peak systolic velocity (PSV) and end-diastolic velocity (EDV) of the ophthalmic artery (OA), central retinal artery (CRA), and temporal posterior ciliary artery (tPCA) were measured with color Doppler imaging, and systolic/diastolic ratio, resistivity index (RI), and pulsatility index (PI) were computed in 42 patients with anisometropic amblyopia. The mean PSV of OA, CRA, and tPCA in amblyopic and fellow eyes were 62.69 ± 24.04, 62.64 ± 20.18; 9.28 ± 3.71, 10.27 ± 4.18; 10.81 ± 4.59, 11.28 ± 4.91, respectively. The mean EDV of OA, CRA, and tPCA in amblyopic and fellow eyes were 15.87 ± 11.31, 14.52 ± 6.54; 2.48 ± 1.17, 2.62 ± 2.06; 3.04 ± 2.34, 3.14 ± 2.18, respectively. The mean RI of OA, CRA, and tPCA in amblyopic and fellow eyes were 0.76 ± 0.08, 0.76 ± 0.08; 0.72 ± 0.08, 0.74 ± 0.95; 0.72 ± 0.09, 0.72 ± 0.08, respectively. The mean PI of OA, CRA, and tPCA in amblyopic and fellow eyes were 1.77 ± 0.42, 1.81 ± 0.46; 01.58 ± 0.42, 1.59 ± 0.43; 1.54 ± 0.43, 1.58 ± 0.49, respectively. There was no statistically significant difference in any of the measured parameters between the amblyopic and fellow eyes. Anisometropic amblyopia did not cause any change in retrobulbar blood flow in amblyopic eyes.
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http://dx.doi.org/10.1007/s10792-012-9572-y | DOI Listing |
Sci Rep
January 2025
Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, BC, Canada.
People with amblyopia show deficits in global motion perception, especially at slow speeds. These observers are also known to have unstable fixation when viewing stationary fixation targets, relative to healthy controls. It is possible that poor fixation stability during motion viewing interferes with the fidelity of the input to motion-sensitive neurons in visual cortex.
View Article and Find Full Text PDFMedicina (Kaunas)
January 2025
Division of Ophthalmology, Department of Special Surgery, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
: Amblyopia is a condition where children undergo unilateral or bilateral vision loss due to a variety of disorders that impact the visual pathway. The assessment of retinal nerve fiber layer (RNFL) thickness in amblyopia has made optical coherence tomography (OCT) a useful technique for studying the pathophysiology of this condition. This study was conducted to assess OCT results for various forms of amblyopia, including macular thickness and peripapillary RNFL thickness.
View Article and Find Full Text PDFJ Neurosci
January 2025
Department of Ophthalmology, Harvard Medical School, Boston, MA, United States.
We employed high-resolution fMRI to distinguish the impacts of anisometropia and strabismus amblyopia on the evoked ocular dominance (OD) response. Sixteen amblyopic participants (8 females) plus 8 individuals with normal vision (1 female), participated in this study for whom, we measured the difference between the response to stimulation of the two eyes, across areas V1-V4.In controls, the evoked OD response formed the expected striped pattern within V1.
View Article and Find Full Text PDFPhotodiagnosis Photodyn Ther
January 2025
Department of Ophthalmology, Fuyang Hospital Affiliated to Bengbu Medical University(Fuyang People's Hospital), Fuyang, 236400, Anhui Province, China. Electronic address:
Purpose: To evaluate optic disc and macular microvasculature changes in children with anisometropic amblyopia before and after treatment.
Methods: In all, 60 children with unilateral anisometropic amblyopia between the ages of 6 and 12 were randomly selected from the ophthalmology clinic of Fuyang People's Hospital, while 60 children with non-amblyopia in the same age range were randomly selected as a normal control group. The right eye was uniformly taken in the control group with at least 6 months of follow-up.
Taiwan J Ophthalmol
June 2024
Department of Vitreo-Retina, Sankara Eye Hospital, Shimoga, Karnataka, India.
Purpose: The purpose of this study was to analyze choroidal thickness (CT), along with macular thickness (MT), peripapillary retinal nerve fiber layer thickness (RNFLT), and macular vascular density (MVD) using swept-source optical coherence tomography (SS-OCT) in children with unilateral amblyopia, and compare the same with normal fellow eyes and normal eyes of normal children before and following occlusion therapy.
Materials And Methods: This was a prospective, longitudinal study of 60 children (4-18 years); 30 children had unilateral amblyopia and remaining 30 were normal. Group 1 consisted of 30 amblyopic eyes of children with unilateral amblyopia; Group 2 consisted of 30 fellow normal eyes of Group 1; Group 3 consisted of normal eyes of normal children.
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